BS8586

antibody from Bioworld Technology, Inc
Targeting: HOXB7 HOX2, HOX2C
Provider product page for BS8586
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8586 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HOXB7 polyclonal antibody
Antibody type
Polyclonal
Antigen
Homeobox protein Hox-B7; Homeobox protein HHO.C1; Homeobox protein Hox-2C; HOXB7; HOX2C
Description
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. A segment of the HoxB7 proximal promoter drives renal expression of reporter genes specifically in the ureteric bud and collecting ducts. Expression levels of HoxB7 are lower in lymph node metastasis-positive cancer tissues than negative cancer tissues. These results suggest that aberrant expression of HOX genes is related to the development of breast cancer and malignant behavior of cancer cells.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HOXB7 protein structure - BS8586 shown in red.