Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8586 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- HOXB7 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Homeobox protein Hox-B7; Homeobox protein HHO.C1; Homeobox protein Hox-2C; HOXB7; HOX2C
- Description
- The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. A segment of the HoxB7 proximal promoter drives renal expression of reporter genes specifically in the ureteric bud and collecting ducts. Expression levels of HoxB7 are lower in lymph node metastasis-positive cancer tissues than negative cancer tissues. These results suggest that aberrant expression of HOX genes is related to the development of breast cancer and malignant behavior of cancer cells.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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