Tissue expression
Cell line expression
Protein structure
BTK
Bruton tyrosine kinaseAGMX1, ATK, IMD1, PSCTK1, XLA
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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OriGene | ![]() |
1 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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Novus Biologicals | ![]() |
3 references | Polyclonal |
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antibodies-online | ![]() |
3 references | Monoclonal |
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