BS8518

antibody from Bioworld Technology, Inc
Targeting: C1R
Provider product page for BS8518
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8518 - Provider product page
Provider
Bioworld Technology, Inc
Product name
C1R polyclonal antibody
Antibody type
Polyclonal
Antigen
Complement C1r subcomponent; Complement component 1 subcomponent r; Complement C1r subcomponent light chain; C1R
Description
The complement component proteins, C1, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation, and cellular chemotaxis. C1q, together with proenzymes C1r and C1s, yield C1, the first component of the classical pathways of the serum complement system. C1 consists of a calcium dependent trimolecular complex of C1r, C1s and C1q in a 2:2:1 ratio. C1r is a dimer formed of two identical chains that are activated by cleavage into two chains, A and B.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
C1R protein structure - BS8518 shown in red.