Antibody data
- Antibody Data
- Antigen structure
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- Product number
- NB100-63270 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-63270, RRID:AB_960758
- Product name
- Mouse Monoclonal Complement C7 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. NB100-63270 recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that this antibody does not recognise membrane bound complement membrane attack complex. This antibody inhibits lysis of sensitised sheep erythrocytes.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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