PRB3

This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the ""Long"" allele. The protein isoforms encoded by this gene are recognized as the ""first line of oral defense"" against the detrimental effects of polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Nov 2015]

Description

Proline rich protein BstNI subfamily 3

Tissue specificity

Tissue enriched (salivary gland)

Predicted location

Secreted to digestive system

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

12 (11265924 - 11269805)

Ensembl ID

ENSG00000197870  (ver. 103.38)

Orthologs

-

UniProt

Q04118

neXtProt

NX_Q04118

Human splice variants

Protein structure