Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN362025 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362025, RRID:AB_10953912
- Product name
- anti-Epidermal Growth Factor Receptor (EGFR) (pSer1070) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer1070 (R-Y-S (p) -S-D) derived from Human EGFR. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer1070
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation.
Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor.
Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism.
Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo.
Feinmesser RL, Wicks SJ, Taverner CJ, Chantry A
The Journal of biological chemistry 1999 Jun 4;274(23):16168-73
The Journal of biological chemistry 1999 Jun 4;274(23):16168-73
Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor.
Gamou S, Shimizu N
FEBS letters 1995 Jan 3;357(2):161-4
FEBS letters 1995 Jan 3;357(2):161-4
Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism.
Gamou S, Shimizu N
Journal of cellular physiology 1994 Jan;158(1):151-9
Journal of cellular physiology 1994 Jan;158(1):151-9
Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo.
Heisermann GJ, Gill GN
The Journal of biological chemistry 1988 Sep 15;263(26):13152-8
The Journal of biological chemistry 1988 Sep 15;263(26):13152-8
No comments: Submit comment
No validations: Submit validation data