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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN358328 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Epidermal Growth Factor Receptor (EGFR) (pTyr1125) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pTyr1125
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references A basic peptide within the juxtamembrane region is required for EGF receptor dimerization.
Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells.
EGF signalling amplification induced by dynamic clustering of EGFR.
Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor.
Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells.
Aifa S, Aydin J, Nordvall G, Lundström I, Svensson SP, Hermanson O
Experimental cell research 2005 Jan 1;302(1):108-14
Experimental cell research 2005 Jan 1;302(1):108-14
Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells.
Kuribayashi A, Kataoka K, Kurabayashi T, Miura M
Endocrinology 2004 Nov;145(11):4976-84
Endocrinology 2004 Nov;145(11):4976-84
EGF signalling amplification induced by dynamic clustering of EGFR.
Ichinose J, Murata M, Yanagida T, Sako Y
Biochemical and biophysical research communications 2004 Nov 19;324(3):1143-9
Biochemical and biophysical research communications 2004 Nov 19;324(3):1143-9
Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor.
Adams TE, McKern NM, Ward CW
Growth factors (Chur, Switzerland) 2004 Jun;22(2):89-95
Growth factors (Chur, Switzerland) 2004 Jun;22(2):89-95
Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells.
Kapoor GS, Zhan Y, Johnson GR, O'Rourke DM
Molecular and cellular biology 2004 Jan;24(2):823-36
Molecular and cellular biology 2004 Jan;24(2):823-36
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