Tissue expression
Cell line expression
Protein structure
SPANXA1
Sperm protein associated with the nucleus, X-linked, family member A1CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Invitrogen Antibodies | 19527-1-AP | Polyclonal |
WB
ICC
IHC
|
||
FineTest Biotech | FNab08149 | Polyclonal |
WB
EL
ICC
IHC |
||
Biorbyt | orb395599 | Polyclonal |
WB
EL
ICC
IHC |
||
antibodies-online | ABIN721675 | Polyclonal |
ICC
IHC |
||
Bioss | bs-7012R | Polyclonal |
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider