FNab02849

antibody from FineTest Biotech

Targeting: ERLIN2 C8orf2, Erlin-2, NET32, SPFH2, SPG18

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab02849 - Provider product page
Provider: FineTest Biotech
Product name: ERLIN2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ER lipid raft associated 2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ERLIN2 protein structure - FNab02849 shown in red.