ABIN362476

antibody from antibodies-online

Targeting: PTK2 FADK, FAK, FAK1, PPP1R71

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362476

Provider

antibodies-online

Product name

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr577) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr 576, pTyr577 (S-T-Y (p) -Y (p) -K-A) derived from Human FAK. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr577

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement.

Parsons JT, Martin KH, Slack JK, Taylor JM, Weed SA
Oncogene 2000 Nov 20;19(49):5606-13

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Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding.

Kaplan DH, Greenlund AC, Tanner JW, Shaw AS, Schreiber RD
The Journal of biological chemistry 1996 Jan 5;271(1):9-12

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT
Molecular and cellular biology 1994 Mar;14(3):1680-8

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

Cobb BS, Schaller MD, Leu TH, Parsons JT
Molecular and cellular biology 1994 Jan;14(1):147-55