ABIN968663

antibody from antibodies-online

Targeting: PTK2 FADK, FAK, FAK1, PPP1R71

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN968663

Provider

antibodies-online

Product name

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr397) antibody

Antibody type

Monoclonal

Antigen

Human FAK (pY397)

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

pTyr397

Isotype

IgG

Antibody clone number

18

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

v-Src induces tyrosine phosphorylation of focal adhesion kinase independently of tyrosine 397 and formation of a complex with Src.

McLean GW, Fincham VJ, Frame MC
The Journal of biological chemistry 2000 Jul 28;275(30):23333-9

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Phosphospecific antibodies reveal focal adhesion kinase activation loop phosphorylation in nascent and mature focal adhesions and requirement for the autophosphorylation site.

Ruest PJ, Roy S, Shi E, Mernaugh RL, Hanks SK
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000 Jan;11(1):41-8

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Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

Calalb MB, Zhang X, Polte TR, Hanks SK
Biochemical and biophysical research communications 1996 Nov 21;228(3):662-8