Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- AF-451-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal CCL4/MIP-1 beta Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects CCL4/MIP-1 beta in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) MIP-1 beta and recombinant mouse (rm) MIP-1 alpha is observed. This antibody will not neutralize the biological activity of rmMIP-1 alpha . In the chemotaxis assay this antibody will partially neutralize rhMIP-1 alpha and rhMIP-1 beta at a 10-30 fold higher IgG concentration.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Recruitment of CD103(+) dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy.
IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury.
Comprehensive assessment of chemokine expression profiles by flow cytometry.
Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process.
CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process.
CCL4 protects from type 1 diabetes by altering islet beta-cell-targeted inflammatory responses.
CC chemokines mediate leukocyte trafficking into the central nervous system during murine neurocysticercosis: role of gamma delta T cells in amplification of the host immune response.
CC chemokines mediate leukocyte trafficking into the central nervous system during murine neurocysticercosis: role of gamma delta T cells in amplification of the host immune response.
Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
Williford JM, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell TM, Potin L, Swartz MA, Hubbell JA
Science advances 2019 Dec;5(12):eaay1357
Science advances 2019 Dec;5(12):eaay1357
IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury.
Thaney VE, O'Neill AM, Hoefer MM, Maung R, Sanchez AB, Kaul M
Scientific reports 2017 Apr 20;7:46514
Scientific reports 2017 Apr 20;7:46514
Comprehensive assessment of chemokine expression profiles by flow cytometry.
Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D
The Journal of clinical investigation 2010 Mar;120(3):907-23
The Journal of clinical investigation 2010 Mar;120(3):907-23
Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
The Journal of experimental medicine 2008 Sep 1;205(9):2075-84
The Journal of experimental medicine 2008 Sep 1;205(9):2075-84
CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process.
Wu Y, Li YY, Matsushima K, Baba T, Mukaida N
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6384-93
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6384-93
CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process.
Wu Y, Li YY, Matsushima K, Baba T, Mukaida N
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6384-93
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6384-93
CCL4 protects from type 1 diabetes by altering islet beta-cell-targeted inflammatory responses.
Meagher C, Arreaza G, Peters A, Strathdee CA, Gilbert PA, Mi QS, Santamaria P, Dekaban GA, Delovitch TL
Diabetes 2007 Mar;56(3):809-17
Diabetes 2007 Mar;56(3):809-17
CC chemokines mediate leukocyte trafficking into the central nervous system during murine neurocysticercosis: role of gamma delta T cells in amplification of the host immune response.
Cardona AE, Gonzalez PA, Teale JM
Infection and immunity 2003 May;71(5):2634-42
Infection and immunity 2003 May;71(5):2634-42
CC chemokines mediate leukocyte trafficking into the central nervous system during murine neurocysticercosis: role of gamma delta T cells in amplification of the host immune response.
Cardona AE, Gonzalez PA, Teale JM
Infection and immunity 2003 May;71(5):2634-42
Infection and immunity 2003 May;71(5):2634-42
Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
Bless NM, Huber-Lang M, Guo RF, Warner RL, Schmal H, Czermak BJ, Shanley TP, Crouch LD, Lentsch AB, Sarma V, Mulligan MS, Friedl HP, Ward PA
Journal of immunology (Baltimore, Md. : 1950) 2000 Mar 1;164(5):2650-9
Journal of immunology (Baltimore, Md. : 1950) 2000 Mar 1;164(5):2650-9
Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
Bless NM, Huber-Lang M, Guo RF, Warner RL, Schmal H, Czermak BJ, Shanley TP, Crouch LD, Lentsch AB, Sarma V, Mulligan MS, Friedl HP, Ward PA
Journal of immunology (Baltimore, Md. : 1950) 2000 Mar 1;164(5):2650-9
Journal of immunology (Baltimore, Md. : 1950) 2000 Mar 1;164(5):2650-9
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Mouse CCL4/MIP-1ß by Western Blot. Detection of Mouse CCL4/MIP-1ß by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- CCL4/MIP-1ß in Mouse Small Intestine. CCL4/MIP-1ß in Mouse Small Intestine.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chemotaxis Induced by CCL4/MIP-1ß and Neutral-ization by Mouse CCL4/ MIP-1ß Antibody. Chemotaxis Induced by CCL4/MIP-1ß and Neutral-ization by Mouse CCL4/ MIP-1ß Antibody.