STX18

This gene encodes a member of the syntaxin family of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) which is part of a membrane tethering complex that includes other SNAREs and several peripheral membrane proteins, and is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi complex. The encoded protein is important for the organization of the smooth, rough, and exit site ER subdomains. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Description

Syntaxin 18

Tissue specificity

Tissue enhanced (cervix)

Subcell location

Endoplasmic reticulum, Plasma membrane

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (4415742 - 4542346)

Ensembl ID

ENSG00000168818  (ver. 103.38)

Orthologs

Mouse Stx18: ENSMUSG00000029125

UniProt

Q9P2W9

neXtProt

NX_Q9P2W9

Human splice variants
Mouse splice variants

Protein structure