Tissue expression
Cell line expression
Protein structure
TLE3
TLE family member 3, transcriptional corepressorESG, ESG3, GRG3, HsT18976, KIAA1547
This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
Top validated antibodies |
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Proteintech Group | ![]() |
20 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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