Tissue expression
Cell line expression
Protein structure
CCL23
C-C motif chemokine ligand 23Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Top validated antibodies |
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Invitrogen Antibodies | PA5-100686 | 1 references | Polyclonal |
WB
IHC
OA
|
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Biorbyt | orb2211913 | Polyclonal |
WB
ICC
IP
IHC |
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R&D Systems | MAB371 | 2 references | Monoclonal |
WB
FC
BN
|
|
Affinity Biosciences | DF2239 | Polyclonal |
WB
EL
IHC
|
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LSBio | LS-C403030 | Polyclonal |
EL
IHC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider