BS4189

antibody from Bioworld Technology, Inc
Targeting: SYK
Provider product page for BS4189
Western blot
Immunohistochemistry

Antibody data

Product number
BS4189 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Syk (phospho Y525) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyrosine 525.
Description
Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SYK protein structure - BS4189 shown in red.