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Western blot
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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
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- Product number
- 626201 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#626201, RRID:AB_493087
- Product name
- Purified anti-Syk
- Antibody type
- Monoclonal
- Antigen
- Partial recombinant (amino acids 5-360) human Syk
- Description
- Syk is a cytoplasmic 72 kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites. The SYK-01 monoclonal antibody (raised against amino acids 5-360 of human Syk) recognizes human, mouse, and rat and Syk and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Cutting edge: critical role of intracellular osteopontin in antifungal innate immune responses.
Inoue M, Moriwaki Y, Arikawa T, Chen YH, Oh YJ, Oliver T, Shinohara ML
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 1;186(1):19-23
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 1;186(1):19-23
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of extracts from Human PBMC, using anti-Syk, Clone SYK-01.
- Conjugate
- Unconjugated
