AGTO-G075R

antibody from Creative Biolabs

Targeting: CCL16 CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4

No application information provided.

Antibody Data

Product number

AGTO-G075R

Provider

Creative Biolabs

Product name

Anti-CCL16 immunotoxin FD441.8 (IgG)-RTA

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the Anti-CCL16 monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to CCL16 positive cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of Graft-versus-host disease (GVHD).

Reactivity

Human

Host

Mouse