BS8875

antibody from Bioworld Technology, Inc
Targeting: RASSF5 Maxp1, NORE1, RAPL
Provider product page for BS8875
Western blot
Immunohistochemistry

Antibody data

Product number
BS8875 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RASSF5 polyclonal antibody
Antibody type
Polyclonal
Antigen
Ras association domain-containing protein 5; New ras effector 1; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RAPL; RASSF5; NORE1, RAPL
Description
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RASSF5 protein structure - BS8875 shown in red.