BS61252

antibody from Bioworld Technology, Inc
Targeting: RDM1 MGC33977, RAD52B
Provider product page for BS61252

Antibody data

Product number
BS61252 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RDM1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human RDM1.
Description
RDM1 (RAD52motif-containing protein 1) is a 284 amino acid protein that is expressed in testis. RDM1 isinvolved in the cellular response to cisplatin, a drug commonly used in chemotherapy. Human RDM1 shares 71.1%and 51.2% amino acid identitywithmouse and chicken RDM1, respectively. RDM1 exists as 11 alternativelyspliced isoforms and only exon 3 iscommon to allvarants. Usage of two translationalstartsites, one in exon 1 and the other in intron 1, produces RDM1 isoformswith either long orshort N termini, and RDM1 isoforms have great diversityin their C termini as well. The RDM1 protein containstwomotifs: amotif found in Rad52, a protein that functions in DNA double-strand breaks and homologousrecombination, and an RNA recognitionmotif (RRM) that is not found in Rad52. The RDM1 gene contains seven coding exons, isconserved in chimpanzee,canine, bovine,mouse, rat, chicken and zebrafish, andmapsto human chromosome 17q12.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RDM1 protein structure - BS61252 shown in red.