Tissue expression
Cell line expression
Protein structure
TMEM185A
Transmembrane protein 185ACXorf13, FAM11A, FRAXF
The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013]
Top validated antibodies |
|||||
Boster Biological Technology | A14846-1 | Polyclonal |
WB
EL
ICC
IHC |
||
Cusabio Biotech Co., Ltd | CSB-PA070028 | Polyclonal |
WB
EL
ICC
IHC |
||
Biorbyt | orb674825 | Polyclonal |
WB
EL
ICC
IHC |
||
GeneTex | GTX87650 | Polyclonal |
WB
EL
ICC
|
||
antibodies-online | ABIN2500408 | Polyclonal |
WB
EL
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider