Tissue expression
Cell line expression
Protein structure
ANAPC10
Anaphase promoting complex subunit 10APC10, DKFZP564L0562, DOC1
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]). [supplied by OMIM, Feb 2011]
Top validated antibodies |
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antibodies-online | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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LSBio | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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