Tissue expression
Cell line expression
Protein structure
DOCK8
Dedicator of cytokinesis 8FLJ00026, FLJ00152, FLJ00346, ZIR8
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Top validated antibodies |
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Proteintech Group | ![]() |
6 references | Polyclonal |
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LSBio | ![]() |
Monoclonal |
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OriGene | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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