NB600-1015
antibody from Novus Biologicals
Targeting: PDPN
aggrus, Gp38, GP40, PA2.26, T1A-2
Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- NB600-1015 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-1015, RRID:AB_2161937
- Product name
- Golden Syrian Hamster Monoclonal Podoplanin Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant.
Activation of podocyte Notch mediates early Wt1 glomerulopathy.
Treatment of acute lung injury by targeting MG53-mediated cell membrane repair.
Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.
Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin.
Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes.
Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node.
Cardiac malformations and myocardial abnormalities in podoplanin knockout mouse embryos: Correlation with abnormal epicardial development.
The role of lymphoid tissue inducer cells in splenic white pulp development.
Nkx2.5-negative myocardium of the posterior heart field and its correlation with podoplanin expression in cells from the developing cardiac pacemaking and conduction system.
A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion.
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors.
Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes.
Loss of neural cell adhesion molecule induces tumor metastasis by up-regulating lymphangiogenesis.
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema.
Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues.
Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus.
Neto LMM, Zufelato N, de Sousa-JĂșnior AA, Trentini MM, da Costa AC, Bakuzis AF, Kipnis A, Junqueira-Kipnis AP
Human vaccines & immunotherapeutics 2018;14(11):2786-2801
Human vaccines & immunotherapeutics 2018;14(11):2786-2801
Activation of podocyte Notch mediates early Wt1 glomerulopathy.
Asfahani RI, Tahoun MM, Miller-Hodges EV, Bellerby J, Virasami AK, Sampson RD, Moulding D, Sebire NJ, Hohenstein P, Scambler PJ, Waters AM
Kidney international 2018 Apr;93(4):903-920
Kidney international 2018 Apr;93(4):903-920
Treatment of acute lung injury by targeting MG53-mediated cell membrane repair.
Jia Y, Chen K, Lin P, Lieber G, Nishi M, Yan R, Wang Z, Yao Y, Li Y, Whitson BA, Duann P, Li H, Zhou X, Zhu H, Takeshima H, Hunter JC, McLeod RL, Weisleder N, Zeng C, Ma J
Nature communications 2014 Jul 18;5:4387
Nature communications 2014 Jul 18;5:4387
Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.
Sargent LM, Porter DW, Staska LM, Hubbs AF, Lowry DT, Battelli L, Siegrist KJ, Kashon ML, Mercer RR, Bauer AK, Chen BT, Salisbury JL, Frazer D, McKinney W, Andrew M, Tsuruoka S, Endo M, Fluharty KL, Castranova V, Reynolds SH
Particle and fibre toxicology 2014 Jan 9;11:3
Particle and fibre toxicology 2014 Jan 9;11:3
Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin.
Kabgani N, Grigoleit T, Schulte K, Sechi A, Sauer-Lehnen S, Tag C, Boor P, Kuppe C, Warsow G, Schordan S, Mostertz J, Chilukoti RK, Homuth G, Endlich N, Tacke F, Weiskirchen R, Fuellen G, Endlich K, Floege J, Smeets B, Moeller MJ
PloS one 2012;7(4):e34907
PloS one 2012;7(4):e34907
Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes.
Porter DW, Hubbs AF, Mercer RR, Wu N, Wolfarth MG, Sriram K, Leonard S, Battelli L, Schwegler-Berry D, Friend S, Andrew M, Chen BT, Tsuruoka S, Endo M, Castranova V
Toxicology 2010 Mar 10;269(2-3):136-47
Toxicology 2010 Mar 10;269(2-3):136-47
Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node.
Mahtab EA, Vicente-Steijn R, Hahurij ND, Jongbloed MR, Wisse LJ, DeRuiter MC, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Gittenberger-de Groot AC
Developmental dynamics : an official publication of the American Association of Anatomists 2009 Jan;238(1):183-93
Developmental dynamics : an official publication of the American Association of Anatomists 2009 Jan;238(1):183-93
Cardiac malformations and myocardial abnormalities in podoplanin knockout mouse embryos: Correlation with abnormal epicardial development.
Mahtab EA, Wijffels MC, Van Den Akker NM, Hahurij ND, Lie-Venema H, Wisse LJ, Deruiter MC, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Gittenberger-De Groot AC
Developmental dynamics : an official publication of the American Association of Anatomists 2008 Mar;237(3):847-57
Developmental dynamics : an official publication of the American Association of Anatomists 2008 Mar;237(3):847-57
The role of lymphoid tissue inducer cells in splenic white pulp development.
Withers DR, Kim MY, Bekiaris V, Rossi SW, Jenkinson WE, Gaspal F, McConnell F, Caamano JH, Anderson G, Lane PJ
European journal of immunology 2007 Nov;37(11):3240-5
European journal of immunology 2007 Nov;37(11):3240-5
Nkx2.5-negative myocardium of the posterior heart field and its correlation with podoplanin expression in cells from the developing cardiac pacemaking and conduction system.
Gittenberger-de Groot AC, Mahtab EA, Hahurij ND, Wisse LJ, Deruiter MC, Wijffels MC, Poelmann RE
Anatomical record (Hoboken, N.J. : 2007) 2007 Jan;290(1):115-22
Anatomical record (Hoboken, N.J. : 2007) 2007 Jan;290(1):115-22
A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion.
Hara T, Katakai T, Lee JH, Nambu Y, Nakajima-Nagata N, Gonda H, Sugai M, Shimizu A
International immunology 2006 Feb;18(2):301-11
International immunology 2006 Feb;18(2):301-11
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors.
Schacht V, Dadras SS, Johnson LA, Jackson DG, Hong YK, Detmar M
The American journal of pathology 2005 Mar;166(3):913-21
The American journal of pathology 2005 Mar;166(3):913-21
Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes.
Katakai T, Hara T, Sugai M, Gonda H, Shimizu A
The Journal of experimental medicine 2004 Sep 20;200(6):783-95
The Journal of experimental medicine 2004 Sep 20;200(6):783-95
Loss of neural cell adhesion molecule induces tumor metastasis by up-regulating lymphangiogenesis.
Crnic I, Strittmatter K, Cavallaro U, Kopfstein L, Jussila L, Alitalo K, Christofori G
Cancer research 2004 Dec 1;64(23):8630-8
Cancer research 2004 Dec 1;64(23):8630-8
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema.
Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M
The EMBO journal 2003 Jul 15;22(14):3546-56
The EMBO journal 2003 Jul 15;22(14):3546-56
Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues.
Farr AG, Berry ML, Kim A, Nelson AJ, Welch MP, Aruffo A
The Journal of experimental medicine 1992 Nov 1;176(5):1477-82
The Journal of experimental medicine 1992 Nov 1;176(5):1477-82
Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus.
Farr A, Nelson A, Hosier S
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992 May;40(5):651-64
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992 May;40(5):651-64
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Podoplanin Antibody (8.1.1) [NB600-1015] - Analysis of Podoplanin in mouse kidney tissue extract.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Podoplanin Antibody (8.1.1) [NB600-1015] - Analysis of Podoplanin in mouse mammary gland after MDA-MB-231 orthotopic transplantation. Image courtesy of product review by Luana Schito.