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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [24]
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- Western blot [2]
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- Product number
- GTX100458 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX100458, RRID:AB_1950936
- Product name
- MMP9 antibody [N2C1], Internal
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Bovine
- Host
- Rabbit
Submitted references Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer.
Upregulation of LGALS1 is associated with oral cancer metastasis.
Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress.
Proangiogenic functions of an RGD-SLAY-containing osteopontin icosamer peptide in HUVECs and in the postischemic brain.
Transforming growth factor alpha promotes tumorigenesis and regulates epithelial-mesenchymal transition modulation in colon cancer.
The invasiveness of human cervical cancer associated to the function of Na(V)1.6 channels is mediated by MMP-2 activity.
MicroRNA-194 modulates epithelial-mesenchymal transition in human colorectal cancer metastasis.
Epidermal growth factor-induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin.
Senescent tumor cells lead the collective invasion in thyroid cancer.
miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9.
3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways.
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion.
Inhibition of human colorectal cancer metastasis by notoginsenoside R1, an important compound from Panax notoginseng.
Treponema pallidum flagellins stimulate MMP-9 and MMP-13 expression via TLR5 and MAPK/NF-κB signaling pathways in human epidermal keratinocytes.
Effects of Panax notoginseng on the Metastasis of Human Colorectal Cancer Cells.
The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1.
Mycobacterium tuberculosis Upregulates TNF-α Expression via TLR2/ERK Signaling and Induces MMP-1 and MMP-9 Production in Human Pleural Mesothelial Cells.
Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) prognostic value in lung adenocarcinoma.
Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA.
Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis.
Inhibition of matrix metalloproteinase activity reverses corneal endothelial-mesenchymal transition.
Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κB-dependent MMP-9 and epithelial-mesenchymal transition expressions.
PRMT7 induces epithelial-to-mesenchymal transition and promotes metastasis in breast cancer.
Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells.
Fukushima R, Kasamatsu A, Nakashima D, Higo M, Fushimi K, Kasama H, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K
Journal of Cancer 2018;9(18):3326-3333
Journal of Cancer 2018;9(18):3326-3333
Upregulation of LGALS1 is associated with oral cancer metastasis.
Li JM, Tseng CW, Lin CC, Law CH, Chien YA, Kuo WH, Chou HC, Wang WC, Chan HL
Therapeutic advances in medical oncology 2018;10:1758835918794622
Therapeutic advances in medical oncology 2018;10:1758835918794622
Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress.
Tsai TH, Lin CJ, Chua S, Chung SY, Chen SM, Lee CH, Hang CL
International journal of molecular sciences 2018 Oct 10;19(10)
International journal of molecular sciences 2018 Oct 10;19(10)
Proangiogenic functions of an RGD-SLAY-containing osteopontin icosamer peptide in HUVECs and in the postischemic brain.
Lee H, Jin YC, Kim SW, Kim ID, Lee HK, Lee JK
Experimental & molecular medicine 2018 Jan 19;50(1):e430
Experimental & molecular medicine 2018 Jan 19;50(1):e430
Transforming growth factor alpha promotes tumorigenesis and regulates epithelial-mesenchymal transition modulation in colon cancer.
Yu CY, Chang WC, Zheng JH, Hung WH, Cho EC
Biochemical and biophysical research communications 2018 Dec 2;506(4):901-906
Biochemical and biophysical research communications 2018 Dec 2;506(4):901-906
The invasiveness of human cervical cancer associated to the function of Na(V)1.6 channels is mediated by MMP-2 activity.
Lopez-Charcas O, Espinosa AM, Alfaro A, Herrera-Carrillo Z, Ramirez-Cordero BE, Cortes-Reynosa P, Perez Salazar E, Berumen J, Gomora JC
Scientific reports 2018 Aug 29;8(1):12995
Scientific reports 2018 Aug 29;8(1):12995
MicroRNA-194 modulates epithelial-mesenchymal transition in human colorectal cancer metastasis.
Cai HK, Chen X, Tang YH, Deng YC
OncoTargets and therapy 2017;10:1269-1278
OncoTargets and therapy 2017;10:1269-1278
Epidermal growth factor-induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin.
Hsu JY, Chang JY, Chang KY, Chang WC, Chen BK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Oct;31(10):4265-4276
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Oct;31(10):4265-4276
Senescent tumor cells lead the collective invasion in thyroid cancer.
Kim YH, Choi YW, Lee J, Soh EY, Kim JH, Park TJ
Nature communications 2017 May 10;8:15208
Nature communications 2017 May 10;8:15208
miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9.
Su MT, Tsai PY, Tsai HL, Chen YC, Kuo PL
BioFactors (Oxford, England) 2017 Mar;43(2):210-219
BioFactors (Oxford, England) 2017 Mar;43(2):210-219
3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways.
Chao W, Deng JS, Li PY, Liang YC, Huang GJ
Molecules (Basel, Switzerland) 2017 Mar 28;22(4)
Molecules (Basel, Switzerland) 2017 Mar 28;22(4)
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion.
Wang CY, Tsai HL, Syu JS, Chen TY, Su MT
Journal of cellular physiology 2017 Jun;232(6):1467-1477
Journal of cellular physiology 2017 Jun;232(6):1467-1477
Inhibition of human colorectal cancer metastasis by notoginsenoside R1, an important compound from Panax notoginseng.
Lee CY, Hsieh SL, Hsieh S, Tsai CC, Hsieh LC, Kuo YH, Wu CC
Oncology reports 2017 Jan;37(1):399-407
Oncology reports 2017 Jan;37(1):399-407
Treponema pallidum flagellins stimulate MMP-9 and MMP-13 expression via TLR5 and MAPK/NF-κB signaling pathways in human epidermal keratinocytes.
Jiang C, Xu M, Kuang X, Xiao J, Tan M, Xie Y, Xiao Y, Zhao F, Wu Y
Experimental cell research 2017 Dec 1;361(1):46-55
Experimental cell research 2017 Dec 1;361(1):46-55
Effects of Panax notoginseng on the Metastasis of Human Colorectal Cancer Cells.
Hsieh SL, Hsieh S, Kuo YH, Wang JJ, Wang JC, Wu CC
The American journal of Chinese medicine 2016;44(4):851-70
The American journal of Chinese medicine 2016;44(4):851-70
The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1.
Gao Y, Zhao Y, Zhang J, Lu Y, Liu X, Geng P, Huang B, Zhang Y, Lu J
Scientific reports 2016 Jan 27;6:19874
Scientific reports 2016 Jan 27;6:19874
Mycobacterium tuberculosis Upregulates TNF-α Expression via TLR2/ERK Signaling and Induces MMP-1 and MMP-9 Production in Human Pleural Mesothelial Cells.
Chen WL, Sheu JR, Chen RJ, Hsiao SH, Hsiao CJ, Chou YC, Chung CL, Hsiao G
PloS one 2015;10(9):e0137979
PloS one 2015;10(9):e0137979
Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) prognostic value in lung adenocarcinoma.
Ruiz-Morales JM, Dorantes-Heredia R, Arrieta O, Chávez-Tapia NC, Motola-Kuba D
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 May;36(5):3601-10
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 May;36(5):3601-10
Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA.
Tsai CH, Lin LT, Wang CY, Chiu YW, Chou YT, Chiu SJ, Wang HE, Liu RS, Wu CY, Chan PC, Yang MH, Chiou SH, Liao MJ, Lee YJ
Biochimica et biophysica acta 2015 May;1852(5):851-61
Biochimica et biophysica acta 2015 May;1852(5):851-61
Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis.
Yeh CY, Shun CT, Kuo YM, Jung CJ, Hsieh SC, Chiu YL, Chen JW, Hsu RB, Yang CJ, Chia JS
Infection and immunity 2015 Jun;83(6):2202-12
Infection and immunity 2015 Jun;83(6):2202-12
Inhibition of matrix metalloproteinase activity reverses corneal endothelial-mesenchymal transition.
Ho WT, Chang JS, Su CC, Chang SW, Hu FR, Jou TS, Wang IJ
The American journal of pathology 2015 Aug;185(8):2158-67
The American journal of pathology 2015 Aug;185(8):2158-67
Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κB-dependent MMP-9 and epithelial-mesenchymal transition expressions.
Lee WT, Lee TH, Cheng CH, Chen KC, Chen YC, Lin CW
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2015 Apr;78:33-41
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2015 Apr;78:33-41
PRMT7 induces epithelial-to-mesenchymal transition and promotes metastasis in breast cancer.
Yao R, Jiang H, Ma Y, Wang L, Wang L, Du J, Hou P, Gao Y, Zhao L, Wang G, Zhang Y, Liu DX, Huang B, Lu J
Cancer research 2014 Oct 1;74(19):5656-67
Cancer research 2014 Oct 1;74(19):5656-67
Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells.
Hsu HY, Lin JH, Li CJ, Tsang SF, Tsai CH, Chyuan JH, Chiu SJ, Chuang SE
Evidence-based complementary and alternative medicine : eCAM 2012;2012:819632
Evidence-based complementary and alternative medicine : eCAM 2012;2012:819632
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: A431 (GTX27909) B: H1299 7.5% SDS PAGE GTX100458 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Untreated (¡V) and treated (+) MCF-7 whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MMP9 antibody [N2C1], Internal (GTX100458) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of methanol-fixed HeLa, using MMP9(GTX100458) antibody at 1:200 dilution.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- MMP9 antibody [N2C1], Internal detects MMP9 protein at cytosol on AGS xenograft by immunohistochemical analysis. Sample: Paraffin-embedded AGS xenograft. MMP9 antibody [N2C1], Internal (GTX100458) dilution: 1:500.
