FNab04801

antibody from FineTest Biotech

Targeting: ARG1

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab04801 - Provider product page
Provider: FineTest Biotech
Product name: liver Arginase antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical?marker?of hepatocellular differentiation in fine needle aspiration cytology and a marker?of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: arginase, liver
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 4A0
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ARG1 protein structure - FNab04801 shown in red.