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- References [182]
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- Product number
- 13409-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13409-1-AP, RRID:AB_2156308
- Product name
- OCLN
- Antibody type
- Polyclonal
- Antigen
- Recombinant Protein
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
- Concentration
- 40 mg/ml
- Storage
- -20
Submitted references Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff.
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis in mice with changes in gut microbiota.
Gualou Xiebai Decoction ameliorates increased Caco-2 monolayer permeability induced by bile acids via tight junction regulation, oxidative stress suppression and apoptosis reduction.
Influences of Xylitol Consumption at Different Dosages on Intestinal Tissues and Gut Microbiota in Rats.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels.
Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation.
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps.
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Xinhuang Tablets Improve Intestinal Barrier Function via Regulating Epithelial Tight Junctions in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice.
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation.
Polystyrene microplastics induced male reproductive toxicity in mice.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Xianglian Pill ameliorates antibiotic-associated diarrhea by restoring intestinal microbiota and attenuating mucosal damage.
Combination of Mesenchymal Stem Cell and Endothelial Progenitor Cell Infusion Accelerates Injured Intestinal Repair by Regulating Gut Microbiota after Hematopoietic Cell Transplantation.
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model.
Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage.
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Isolation of Mouse Cerebral Microvasculature for Molecular and Single-Cell Analysis.
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Dietary Copper Plays an Important Role in Maintaining Intestinal Barrier Integrity During Alcohol-Induced Liver Disease Through Regulation of the Intestinal HIF-1α Signaling Pathway and Oxidative Stress.
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.
Salmonella Effector SpvB Disrupts Intestinal Epithelial Barrier Integrity for Bacterial Translocation.
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Interferon-β alleviates delayed tPA-induced adverse effects via modulation of MMP3/9 production in ischemic stroke.
Claudin 1 inhibits cell migration and increases intercellular adhesion in triple-negative breast cancer cell line.
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Dl-3-n-butylphthalide attenuates hypoxic-ischemic brain injury through inhibiting endoplasmic reticulum stress-induced cell apoptosis and alleviating blood-brain barrier disruption in newborn rats.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Assessment of oral ciprofloxacin impaired gut barrier integrity on gut bacteria in mice.
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE2/MMP-2 in Mouse Offspring.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia.
A Novel Pharmacological Approach to Enhance the Integrity and Accelerate Restitution of the Intestinal Epithelial Barrier.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice.
Puerarin prevents high-fat diet-induced obesity by enriching Akkermansia muciniphila in the gut microbiota of mice.
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China.
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
Fasudil alleviates LPS-induced lung injury by restoring aquaporin 5 expression and inhibiting inflammation in lungs.
Newly synthesized claudins but not occludin are added to the basal side of the tight junction.
Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells.
SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients.
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation.
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets.
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs.
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins.
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction protein degradation.
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage.
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation.
Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway.
Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage.
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats.
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Pro-apoptotic effect of Δ2-TGZ in "claudin-1-low" triple-negative breast cancer cells: involvement of claudin-1.
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats.
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Oral administration of propionic acid during lactation enhances the colonic barrier function.
Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease.
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.
Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats.
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.
Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice.
Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role.
Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
He Y, Liu Y, Tang J, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff.
Ranftler C, Nagl D, Sparer A, Röhrich A, Freissmuth M, El-Kasaby A, Nasrollahi Shirazi S, Koban F, Tschegg C, Nizet S
PloS one 2021;16(5):e0252211
PloS one 2021;16(5):e0252211
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
He Y, Chen J, Zhang Q, Zhang J, Wang L, Chen X, Molenaar AJ, Sun X
Frontiers in plant science 2021;12:673774
Frontiers in plant science 2021;12:673774
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease.
Tang XH, Melis M, Mai K, Gudas LJ, Trasino SE
Frontiers in pharmacology 2021;12:630557
Frontiers in pharmacology 2021;12:630557
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Qin Q, Chen Y, Li Y, Wei J, Zhou X, Le F, Hu H, Chen T
Frontiers in cellular and infection microbiology 2021;11:719542
Frontiers in cellular and infection microbiology 2021;11:719542
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Guo C, Guo D, Fang L, Sang T, Wu J, Guo C, Wang Y, Wang Y, Chen C, Chen J, Chen R, Wang X
Carbohydrate polymers 2021 Sep 1;267:118231
Carbohydrate polymers 2021 Sep 1;267:118231
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
Xun W, Fu Q, Shi L, Cao T, Jiang H, Ma Z
International immunopharmacology 2021 Oct;99:107989
International immunopharmacology 2021 Oct;99:107989
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Xu SY, Bian HJ, Shu S, Xia SN, Gu Y, Zhang MJ, Xu Y, Cao X
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis in mice with changes in gut microbiota.
Guo M, Liu X, Tan Y, Kang F, Zhu X, Fan X, Wang C, Wang R, Liu Y, Qin X, Jiang M, Wang X
Food & function 2021 Oct 4;12(19):9380-9390
Food & function 2021 Oct 4;12(19):9380-9390
Gualou Xiebai Decoction ameliorates increased Caco-2 monolayer permeability induced by bile acids via tight junction regulation, oxidative stress suppression and apoptosis reduction.
Su J, He Z, Yu Y, Lu M, Wu Z, Zhang D
Journal of bioenergetics and biomembranes 2021 Oct 31;
Journal of bioenergetics and biomembranes 2021 Oct 31;
Influences of Xylitol Consumption at Different Dosages on Intestinal Tissues and Gut Microbiota in Rats.
Zuo QL, Cai X, Zheng XY, Chen DS, Li M, Liu ZQ, Chen KQ, Han FF, Zhu X
Journal of agricultural and food chemistry 2021 Oct 13;69(40):12002-12011
Journal of agricultural and food chemistry 2021 Oct 13;69(40):12002-12011
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels.
Chen Q, Wu Y, Yu Y, Wei J, Huang W
Molecular and cellular biochemistry 2021 May;476(5):2159-2170
Molecular and cellular biochemistry 2021 May;476(5):2159-2170
Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection.
Hu W, Xu D, Zhou Z, Zhu J, Wang D, Tang J
Microbial pathogenesis 2021 May;154:104826
Microbial pathogenesis 2021 May;154:104826
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;
CNS neuroscience & therapeutics 2021 May 13;
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Fang W, Zhao P, Shen A, Liu L, Chen H, Chen Y, Peng J, Sferra TJ, Sankararaman S, Luo Y, Ke X
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation.
Sang T, Guo C, Guo D, Wu J, Wang Y, Wang Y, Chen J, Chen C, Wu K, Na K, Li K, Fang L, Guo C, Wang X
Carbohydrate polymers 2021 Mar 15;256:117594
Carbohydrate polymers 2021 Mar 15;256:117594
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps.
Dong W, Liu D, Zhang T, You Q, Huang F, Wu J
Ecotoxicology and environmental safety 2021 Jun 1;215:112161
Ecotoxicology and environmental safety 2021 Jun 1;215:112161
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Liu FY, Wen J, Hou J, Zhang SQ, Sun CB, Zhou LC, Yin W, Pang WL, Wang C, Ying Y, Han SS, Yan JY, Li CX, Yuan JL, Xing HJ, Yang ZS
International immunopharmacology 2021 Jul;96:107758
International immunopharmacology 2021 Jul;96:107758
TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy.
Liu Y, Li L, Pan N, Gu J, Qiu Z, Cao G, Dou Y, Dong L, Shuai J, Sang A
Biochemical and biophysical research communications 2021 Jul 5;561:143-150
Biochemical and biophysical research communications 2021 Jul 5;561:143-150
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Cao YY, Wang Z, Wang ZH, Jiang XG, Lu WH
International immunopharmacology 2021 Jan;90:107218
International immunopharmacology 2021 Jan;90:107218
Xinhuang Tablets Improve Intestinal Barrier Function via Regulating Epithelial Tight Junctions in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice.
Wu M, Shen A, Chen Y, Liu L, Li L, Sankararaman S, Chen H, Guan B, Zhan Z, Nan S, Sferra TJ, Peng J
Journal of medicinal food 2021 Jan;24(1):33-39
Journal of medicinal food 2021 Jan;24(1):33-39
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Jia Z, Bao K, Wei P, Yu X, Zhang Y, Wang X, Wang X, Yao L, Li L, Wu P, Yuan W, Wang S, Zheng J, Hua Y, Hong M
Mucosal immunology 2021 Jan;14(1):125-134
Mucosal immunology 2021 Jan;14(1):125-134
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation.
Chan YJ, Liao PL, Tsai CH, Cheng YW, Lin FL, Ho JD, Chen CY, Li CH
Particle and fibre toxicology 2021 Jan 9;18(1):4
Particle and fibre toxicology 2021 Jan 9;18(1):4
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Xianglian Pill ameliorates antibiotic-associated diarrhea by restoring intestinal microbiota and attenuating mucosal damage.
Yang L, Zhang Q, Huang J, Liu D, Lan Y, Yuan L, Chen Q
Journal of ethnopharmacology 2021 Jan 10;264:113377
Journal of ethnopharmacology 2021 Jan 10;264:113377
Combination of Mesenchymal Stem Cell and Endothelial Progenitor Cell Infusion Accelerates Injured Intestinal Repair by Regulating Gut Microbiota after Hematopoietic Cell Transplantation.
Zhu S, Li H, Lv C, Liang J, Liu L, Zhang X, Xu K, Zeng L
Transplantation and cellular therapy 2021 Feb;27(2):152.e1-152.e9
Transplantation and cellular therapy 2021 Feb;27(2):152.e1-152.e9
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Ma J, Shah AM, Wang ZS, Hu R, Zou HW, Wang XY, Zhao SN, Kong XY
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Chen KJ, Chen YL, Ueng SH, Hwang TL, Kuo LM, Hsieh PW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Li J, Zhang L, Wu T, Li Y, Zhou X, Ruan Z
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X
Virulence 2021 Dec;12(1):2296-2313
Virulence 2021 Dec;12(1):2296-2313
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Jiao-Yan Y, Qing-Qing L, Xi L, Mei Z, Ting S, Na H, Wei J, Rui-Tao Z, Peng Y, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Chen Y, Jiang Z, Lei Z, Ping J, Su J
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Ma J, Shah AM, Wang Z, Hu R, Zou H, Wang X, Cao G, Peng Q, Xue B, Wang L, Zhao S, Kong X
PeerJ 2020;8:e9851
PeerJ 2020;8:e9851
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model.
Shi Y, Gao F, Yang X, Liu D, Han Q, Liu Z, Zhu H, Shen Y
Journal of Alzheimer's disease : JAD 2020;76(1):237-248
Journal of Alzheimer's disease : JAD 2020;76(1):237-248
Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage.
Qi R, Qiu X, Du L, Wang J, Wang Q, Huang J, Liu Z
Frontiers in veterinary science 2020;7:617259
Frontiers in veterinary science 2020;7:617259
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Liu DY, Lou WJ, Zhang DY, Sun SY
BioMed research international 2020;2020:8819195
BioMed research international 2020;2020:8819195
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Isolation of Mouse Cerebral Microvasculature for Molecular and Single-Cell Analysis.
Paraiso HC, Wang X, Kuo PC, Furnas D, Scofield BA, Chang FL, Yen JH, Yu IC
Frontiers in cellular neuroscience 2020;14:84
Frontiers in cellular neuroscience 2020;14:84
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Wu DM, Liu T, Deng SH, Han R, Zhang T, Li J, Xu Y
OncoTargets and therapy 2020;13:3751-3763
OncoTargets and therapy 2020;13:3751-3763
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Hu R, He Z, Liu M, Tan J, Zhang H, Hou DX, He J, Wu S
Journal of animal science and biotechnology 2020;11:92
Journal of animal science and biotechnology 2020;11:92
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Zhang H, Chen Y, Chen Y, Ji S, Jia P, Li Y, Wang T
Journal of animal science and biotechnology 2020;11:52
Journal of animal science and biotechnology 2020;11:52
Dietary Copper Plays an Important Role in Maintaining Intestinal Barrier Integrity During Alcohol-Induced Liver Disease Through Regulation of the Intestinal HIF-1α Signaling Pathway and Oxidative Stress.
Lin H, Chen D, Du Q, Pan T, Tu H, Xu Y, Teng T, Tu J, Li J, Lin Z, Wang X, Xu L, Chen YP
Frontiers in physiology 2020;11:369
Frontiers in physiology 2020;11:369
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Ding F, Wu J, Liu C, Bian Q, Qiu W, Ma Q, Li X, Long M, Zou X, Chen J
Frontiers in pharmacology 2020;11:1069
Frontiers in pharmacology 2020;11:1069
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Ren L, Feng W, Shao J, Ma J, Xu M, Zhu BZ, Zheng N, Liu S
Theranostics 2020;10(14):6384-6398
Theranostics 2020;10(14):6384-6398
Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.
Li X, Liu Y, Wang Y, Li X, Liu X, Guo M, Tan Y, Qin X, Wang X, Jiang M
Frontiers in oncology 2020;10:710
Frontiers in oncology 2020;10:710
Salmonella Effector SpvB Disrupts Intestinal Epithelial Barrier Integrity for Bacterial Translocation.
Sun L, Yang S, Deng Q, Dong K, Li Y, Wu S, Huang R
Frontiers in cellular and infection microbiology 2020;10:606541
Frontiers in cellular and infection microbiology 2020;10:606541
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901
Molecular neurobiology 2020 Sep;57(9):3891-3901
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83
Brain research bulletin 2020 Sep;162:73-83
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Furutama D, Matsuda S, Yamawaki Y, Hatano S, Okanobu A, Memida T, Oue H, Fujita T, Ouhara K, Kajiya M, Mizuno N, Kanematsu T, Tsuga K, Kurihara H
Brain sciences 2020 Sep 27;10(10)
Brain sciences 2020 Sep 27;10(10)
Interferon-β alleviates delayed tPA-induced adverse effects via modulation of MMP3/9 production in ischemic stroke.
Kuo PC, Weng WT, Scofield BA, Furnas D, Paraiso HC, Intriago AJ, Bosi KD, Yu IC, Yen JH
Blood advances 2020 Sep 22;4(18):4366-4381
Blood advances 2020 Sep 22;4(18):4366-4381
Claudin 1 inhibits cell migration and increases intercellular adhesion in triple-negative breast cancer cell line.
Geoffroy M, Kleinclauss A, Kuntz S, Grillier-Vuissoz I
Molecular biology reports 2020 Oct;47(10):7643-7653
Molecular biology reports 2020 Oct;47(10):7643-7653
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Yang Q, Luo L, Sun T, Yang L, Cheng LF, Wang Y, Liu QQ, Liu A, Liu HY, Zhao MG, Wu SX, Feng B
Psychopharmacology 2020 Oct;237(10):3201-3213
Psychopharmacology 2020 Oct;237(10):3201-3213
Dl-3-n-butylphthalide attenuates hypoxic-ischemic brain injury through inhibiting endoplasmic reticulum stress-induced cell apoptosis and alleviating blood-brain barrier disruption in newborn rats.
Fang M, Yuan J, Jiang S, Hu Y, Pan S, Zhu J, Fu X, Jiang H, Lin J, Li P, Lin Z
Brain research 2020 Nov 15;1747:147046
Brain research 2020 Nov 15;1747:147046
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Assessment of oral ciprofloxacin impaired gut barrier integrity on gut bacteria in mice.
Zhu S, Li H, Liang J, Lv C, Zhao K, Niu M, Li Z, Zeng L, Xu K
International immunopharmacology 2020 Jun;83:106460
International immunopharmacology 2020 Jun;83:106460
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Yin J, Zhou C, Yang K, Ren Y, Qiu Y, Xu P, Xiao W, Yang H
Cell biology international 2020 Jun;44(6):1405-1414
Cell biology international 2020 Jun;44(6):1405-1414
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Gao J, Li X, Gao L, Chen H, Baras BH, Liu X, Liu H, Rana A, Gao M, Ruan J
International journal of molecular medicine 2020 Jul;46(1):179-190
International journal of molecular medicine 2020 Jul;46(1):179-190
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE2/MMP-2 in Mouse Offspring.
Ma T, Zhou Y, Xia Y, Meng X, Jin H, Wang B, Chen Y, Qiu J, Wu J, Ding J, Han X, Li D
Environmental science & technology 2020 Jul 7;54(13):8245-8258
Environmental science & technology 2020 Jul 7;54(13):8245-8258
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Sun D, Yang L, Cao H, Shen ZY, Song HL
Cell biology international 2020 Feb;44(2):549-559
Cell biology international 2020 Feb;44(2):549-559
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia.
Li M, Li SC, Dou BK, Zou YX, Han HZ, Liu DX, Ke ZJ, Wang ZF
Acta pharmacologica Sinica 2020 Aug;41(8):1025-1032
Acta pharmacologica Sinica 2020 Aug;41(8):1025-1032
A Novel Pharmacological Approach to Enhance the Integrity and Accelerate Restitution of the Intestinal Epithelial Barrier.
Cao X, Sun L, Lechuga S, Naydenov NG, Feygin A, Ivanov AI
Inflammatory bowel diseases 2020 Aug 20;26(9):1340-1352
Inflammatory bowel diseases 2020 Aug 20;26(9):1340-1352
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Zhang Y, Zhang X, Wei Q, Leng S, Li C, Han B, Bai Y, Zhang H, Yao H
Translational stroke research 2020 Apr;11(2):267-287
Translational stroke research 2020 Apr;11(2):267-287
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice.
He Y, Li X, Yu H, Ge Y, Liu Y, Qin X, Jiang M, Wang X
Frontiers in cellular and infection microbiology 2019;9:393
Frontiers in cellular and infection microbiology 2019;9:393
Puerarin prevents high-fat diet-induced obesity by enriching Akkermansia muciniphila in the gut microbiota of mice.
Wang L, Wu Y, Zhuang L, Chen X, Min H, Song S, Liang Q, Li AD, Gao Q
PloS one 2019;14(6):e0218490
PloS one 2019;14(6):e0218490
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
Hu L, Wu C, Zhang Z, Liu M, Maruthi Prasad E, Chen Y, Wang K
Frontiers in physiology 2019;10:908
Frontiers in physiology 2019;10:908
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China.
Gong Z, Shi X, Bai F, He X, Zhang H, Li Y, Wan Y, Lin Y, Qiu Y, Chen Q, Hu Q, Cao H
Frontiers in microbiology 2019;10:2810
Frontiers in microbiology 2019;10:2810
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Bao K, Yuan W, Zhou Y, Chen Y, Yu X, Wang X, Jia Z, Yu X, Wang X, Yao L, Wang S, Xu Y, Zhang Y, Zheng J, Hong M
Frontiers in pharmacology 2019;10:1698
Frontiers in pharmacology 2019;10:1698
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Luo L, Liu Y, Cai X, Wang Y, Xue J, Zhang J, Yang F
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Li X, Mao M, Zhang Y, Yu K, Zhu W
Biomolecules 2019 Sep 13;9(9)
Biomolecules 2019 Sep 13;9(9)
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
Sun Z, Xie Q, Pan J, Niu N
Renal failure 2019 Nov;41(1):354-362
Renal failure 2019 Nov;41(1):354-362
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling.
Sun X, Yao L, Liang H, Wang D, He Y, Wei Y, Ye L, Wang K, Li L, Chen J, Zhang CY, Xu G, Wang F, Zen K
Mucosal immunology 2019 Nov;12(6):1280-1290
Mucosal immunology 2019 Nov;12(6):1280-1290
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.
He Y, Yu H, Ge Y, Li X, Jiang M, Liu Y, Li X, Wang Y, Guo M, Qin X, Wang X
Biochemical and biophysical research communications 2019 May 28;513(2):426-433
Biochemical and biophysical research communications 2019 May 28;513(2):426-433
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
Zhu Z, Yu J, Lin W, Tang H, Zhang W, Lu B
Molecular medicine reports 2019 Jun;19(6):5177-5184
Molecular medicine reports 2019 Jun;19(6):5177-5184
Fasudil alleviates LPS-induced lung injury by restoring aquaporin 5 expression and inhibiting inflammation in lungs.
Wang JJ, Kong H, Xu J, Wang YL, Wang H, Xie WP
Journal of biomedical research 2019 Jun 4;33(3):156-163
Journal of biomedical research 2019 Jun 4;33(3):156-163
Newly synthesized claudins but not occludin are added to the basal side of the tight junction.
Van Itallie CM, Lidman KF, Tietgens AJ, Anderson JM
Molecular biology of the cell 2019 Jun 1;30(12):1406-1424
Molecular biology of the cell 2019 Jun 1;30(12):1406-1424
Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells.
Zhang Y, Ding X, Miao C, Chen J
BMC anesthesiology 2019 Jul 9;19(1):127
BMC anesthesiology 2019 Jul 9;19(1):127
SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients.
Yu H, Sun J, Zhao C, Wang H, Liu Y, Xiong J, Chang J, Wang M, Wang W, Ye D, Zhou H, Yu T
BMC cancer 2019 Jul 25;19(1):736
BMC cancer 2019 Jul 25;19(1):736
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
Wu P, Gao Y, Shen S, Xue Y, Liu X, Ruan X, Shao L, Liu Y, Wang P
Cell death & disease 2019 Jul 11;10(7):536
Cell death & disease 2019 Jul 11;10(7):536
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Wang J, Tian S, Yu H, Wang J, Zhu W
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
Liao Z, Zhang H, Fan P, Huang Q, Dong K, Qi Y, Song J, Chen L, Liang H, Chen X, Zhang Z, Zhang B
International journal of oncology 2019 Feb;54(2):479-490
International journal of oncology 2019 Feb;54(2):479-490
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM
Nature communications 2019 Feb 8;10(1):660
Nature communications 2019 Feb 8;10(1):660
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
You M, Miao Z, Pan Y, Hu F
European journal of pharmacology 2019 Dec 15;865:172736
European journal of pharmacology 2019 Dec 15;865:172736
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Xu J, Wei G, Wang J, Zhu J, Yu M, Zeng X, Wang H, Xie W, Kong H
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Li X, Dong M, Zhou J, Zhu D, Zhao J, Sheng W
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets.
Wang S, Li H, Du C, Liu Q, Yang D, Chen L, Zhu Q, Wang Z
PeerJ 2018;6:e6060
PeerJ 2018;6:e6060
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Wang Y, Kim R, Gunasekara DB, Reed MI, DiSalvo M, Nguyen DL, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs.
Zhang Y, Zhao X, Zhu Y, Ma J, Ma H, Zhang H
Mediators of inflammation 2018;2018:9416391
Mediators of inflammation 2018;2018:9416391
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, Chen G, Li X, Xiao W, Xu P, Yang H
International journal of biological sciences 2018;14(1):69-77
International journal of biological sciences 2018;14(1):69-77
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, Hong M
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Luo L, Zhou Z, Xue J, Wang Y, Zhang J, Cai X, Liu Y, Yang F
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Liu WT, Lv YJ, Yang RC, Fu JY, Liu L, Wang H, Cao Q, Tan C, Chen HC, Wang XR
Journal of neuroinflammation 2018 Oct 19;15(1):291
Journal of neuroinflammation 2018 Oct 19;15(1):291
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Leng X, Ma J, Liu Y, Shen S, Yu H, Zheng J, Liu X, Liu L, Chen J, Zhao L, Ruan X, Xue Y
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins.
Manthari RK, Tikka C, Ommati MM, Niu R, Sun Z, Wang J, Zhang J, Wang J
Archives of toxicology 2018 Nov;92(11):3255-3275
Archives of toxicology 2018 Nov;92(11):3255-3275
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Wu YY, Li TM, Zang LQ, Liu B, Wang GX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction protein degradation.
Zhao R, Guo Z, Zhang R, Deng C, Xu J, Dong W, Hong Z, Yu H, Situ H, Liu C, Zhuang G
Journal of applied toxicology : JAT 2018 May;38(5):678-687
Journal of applied toxicology : JAT 2018 May;38(5):678-687
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, Sheng B, Li X, Sun L, Yu M, Yang H
International journal of molecular medicine 2018 Mar;41(3):1560-1572
International journal of molecular medicine 2018 Mar;41(3):1560-1572
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
Zhang X, Jiang G, Wu J, Zhou H, Zhang Y, Miao Y, Feng Y, Yu J
Oncology letters 2018 Mar;15(3):3806-3813
Oncology letters 2018 Mar;15(3):3806-3813
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
Shen S, Yu H, Liu X, Liu Y, Zheng J, Wang P, Gong W, Chen J, Zhao L, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Lu M, Wu J, Hao ZW, Shang YK, Xu J, Nan G, Li X, Chen ZN, Bian H
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation.
Deng J, Zeng L, Lai X, Li J, Liu L, Lin Q, Chen Y
Journal of cellular and molecular medicine 2018 Jan;22(1):546-557
Journal of cellular and molecular medicine 2018 Jan;22(1):546-557
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.
Dong Y, Wang Z, Qin Z, Cao J, Chen Y
Journal of molecular histology 2018 Feb;49(1):85-97
Journal of molecular histology 2018 Feb;49(1):85-97
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Yang S, Jin H, Zhao Z
Neurological research 2018 Feb;40(2):117-121
Neurological research 2018 Feb;40(2):117-121
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage.
Adegoke EO, Xue W, Machebe NS, Adeniran SO, Hao W, Chen W, Han Z, Guixue Z, Peng Z
Ecotoxicology and environmental safety 2018 Dec 30;166:165-175
Ecotoxicology and environmental safety 2018 Dec 30;166:165-175
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Wang S, Xie T, Sun S, Wang K, Liu B, Wu X, Ding W
Scientific reports 2018 Dec 12;8(1):17788
Scientific reports 2018 Dec 12;8(1):17788
Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation.
Zhao M, Xiong X, Ren K, Xu B, Cheng M, Sahu C, Wu K, Nie Y, Huang Z, Blumberg RS, Han X, Ruan HB
EMBO molecular medicine 2018 Aug;10(8)
EMBO molecular medicine 2018 Aug;10(8)
Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway.
Manthari RK, Tikka C, Ommati MM, Niu R, Sun Z, Wang J, Zhang J, Wang J
Journal of agricultural and food chemistry 2018 Aug 15;66(32):8602-8614
Journal of agricultural and food chemistry 2018 Aug 15;66(32):8602-8614
Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage.
Qie X, Wen D, Guo H, Xu G, Liu S, Shen Q, Liu Y, Zhang W, Cong B, Ma C
Frontiers in pharmacology 2017;8:639
Frontiers in pharmacology 2017;8:639
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Li L, Wang N, Jin Q, Wu Q, Liu Y, Wang Y
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
Zhang QY, Wang ZJ, Sun DM, Wang Y, Xu P, Wu WJ, Liu XH, Zhu YZ
Oxidative medicine and cellular longevity 2017;2017:7150376
Oxidative medicine and cellular longevity 2017;2017:7150376
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Yang S, Mei S, Jin H, Zhu B, Tian Y, Huo J, Cui X, Guo A, Zhao Z
PloS one 2017;12(10):e0187017
PloS one 2017;12(10):e0187017
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Zhang X, Zhou H, Cai L, Fan C, Liu Y, Wang L, Li Q, Miao Y
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats.
Fang M, Jiang H, Ye L, Cai C, Hu Y, Pan S, Li P, Xiao J, Lin Z
Oncotarget 2017 Sep 26;8(43):75308-75325
Oncotarget 2017 Sep 26;8(43):75308-75325
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Zhang X, Liu Y, Fan C, Wang L, Li A, Zhou H, Cai L, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Sep 26;8(43):75102-75113
Oncotarget 2017 Sep 26;8(43):75102-75113
Pro-apoptotic effect of Δ2-TGZ in "claudin-1-low" triple-negative breast cancer cells: involvement of claudin-1.
Geoffroy M, Kleinclauss A, Grandemange S, Hupont S, Boisbrun M, Flament S, Grillier-Vuissoz I, Kuntz S
Breast cancer research and treatment 2017 Oct;165(3):517-527
Breast cancer research and treatment 2017 Oct;165(3):517-527
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Wang J, Fu X, Zhang D, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Wang M, Liu X, Chen X, Zang W, Yang Q, Wang J
Neuroscience 2017 Nov 19;364:202-211
Neuroscience 2017 Nov 19;364:202-211
Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.
Li CH, Liu CW, Tsai CH, Peng YJ, Yang YH, Liao PL, Lee CC, Cheng YW, Kang JJ
Archives of toxicology 2017 May;91(5):2165-2178
Archives of toxicology 2017 May;91(5):2165-2178
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Li Y, Xu B, Xu M, Chen D, Xiong Y, Lian M, Sun Y, Tang Z, Wang L, Jiang C, Lin Y
Pharmacological research 2017 May;119:137-148
Pharmacological research 2017 May;119:137-148
Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats.
Hu Y, Wang Z, Pan S, Zhang H, Fang M, Jiang H, Zhang H, Gao Z, Xu K, Li Z, Xiao J, Lin Z
Oncotarget 2017 May 9;8(19):31638-31654
Oncotarget 2017 May 9;8(19):31638-31654
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Han J, Li JH, Bai G, Shen GS, Chen J, Liu JN, Wang S, Liu XJ
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
Oral administration of propionic acid during lactation enhances the colonic barrier function.
Xia Z, Han Y, Wang K, Guo S, Wu D, Huang X, Li Z, Zhu L
Lipids in health and disease 2017 Mar 23;16(1):62
Lipids in health and disease 2017 Mar 23;16(1):62
Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.
He F, Duan X, Dai R, Li Y, Lin Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Zhou H, Zhang Y, Cai L, Jiang G, Li A, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Jun 13;8(24):38863-38875
Oncotarget 2017 Jun 13;8(24):38863-38875
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Wang Y, DiSalvo M, Gunasekara DB, Dutton J, Proctor A, Lebhar MS, Williamson IA, Speer J, Howard RL, Smiddy NM, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Du J, Zhang X, Zhou H, Miao Y, Han Y, Han Q, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, Wang E, Zhang Y
Oncotarget 2017 Feb 21;8(8):13357-13366
Oncotarget 2017 Feb 21;8(8):13357-13366
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Zhang X, Cai L, Zhou H, Liu Y, Fan C, Wang L, Li A, Miao Y, Li Q, Qiu X, Wang E
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.
Wu J, He Z, Yang XM, Li KL, Wang DL, Sun FL
Cancer letters 2017 Aug 1;400:18-29
Cancer letters 2017 Aug 1;400:18-29
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Yang R, Liu W, Miao L, Yang X, Fu J, Dou B, Cai A, Zong X, Tan C, Chen H, Wang X
Oncotarget 2016 Sep 27;7(39):63839-63855
Oncotarget 2016 Sep 27;7(39):63839-63855
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G
Journal of virology 2016 Nov 1;90(21):9632-9643
Journal of virology 2016 Nov 1;90(21):9632-9643
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.
Yamamoto S, Fukuhara T, Ono C, Uemura K, Kawachi Y, Shiokawa M, Mori H, Wada M, Shima R, Okamoto T, Hiraga N, Suzuki R, Chayama K, Wakita T, Matsuura Y
PLoS pathogens 2016 May;12(5):e1005610
PLoS pathogens 2016 May;12(5):e1005610
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Han J, Xu Y, Yang D, Yu N, Bai Z, Bian L
Asian-Australasian journal of animal sciences 2016 Jan;29(1):134-41
Asian-Australasian journal of animal sciences 2016 Jan;29(1):134-41
Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease.
Gong Y, Li H, Li Y
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Feb;36(2):75-85
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Feb;36(2):75-85
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Wang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao J
Molecular neurobiology 2016 Dec;53(10):7298-7311
Molecular neurobiology 2016 Dec;53(10):7298-7311
Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.
Lin CW, Wang LK, Wang SP, Chang YL, Wu YY, Chen HY, Hsiao TH, Lai WY, Lu HH, Chang YH, Yang SC, Lin MW, Chen CY, Hong TM, Yang PC
Nature communications 2016 Dec 22;7:13867
Nature communications 2016 Dec 22;7:13867
Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.
Zhang J, Li Z, Qie M, Zheng R, Shetty J, Wang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2016 Aug;94:103-11
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2016 Aug;94:103-11
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats.
Lu D, Qu Y, Shi F, Feng D, Tao K, Gao G, He S, Zhao T
Biochemical and biophysical research communications 2016 Aug 19;477(2):209-14
Biochemical and biophysical research communications 2016 Aug 19;477(2):209-14
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Yu X, Zhang X, Zhang Y, Jiang G, Mao X, Jin F
Oncotarget 2015 Sep 22;6(28):25034-45
Oncotarget 2015 Sep 22;6(28):25034-45
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.
Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L, Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, Truchetet F, Rades D, Sorokin LM, Schmidt-Supprian M, Bedell BJ, Pasparakis M, Balschun D, D'Hooge R, Löscher W, Hamel E, Schwaninger M
The Journal of experimental medicine 2015 Sep 21;212(10):1529-49
The Journal of experimental medicine 2015 Sep 21;212(10):1529-49
Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice.
Li CH, Shyu MK, Jhan C, Cheng YW, Tsai CH, Liu CW, Lee CC, Chen RM, Kang JJ
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):192-203
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):192-203
Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role.
Zhang X, Zhao X, Shao S, Zuo X, Ning Q, Luo M, Gu S, Zhao X
International journal of oncology 2015 Mar;46(3):1141-8
International journal of oncology 2015 Mar;46(3):1141-8
Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.
Shao S, Zhao X, Zhang X, Luo M, Zuo X, Huang S, Wang Y, Gu S, Zhao X
Molecular cancer 2015 Feb 3;14:28
Molecular cancer 2015 Feb 3;14:28
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Zhang X, Miao Y, Yu X, Zhang Y, Jiang G, Liu Y, Yu J, Han Q, Zhao H, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ning Q, Liu C, Hou L, Meng M, Zhang X, Luo M, Shao S, Zuo X, Zhao X
PloS one 2013;8(6):e65217
PloS one 2013;8(6):e65217
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Occludin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Occludin. This antibody recognizes human,mouse,rat antigen. The Occludin antibody has been validated for the following applications: ELISA, WB analysis.
