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- Antibody Data
- Antigen structure
- References [433]
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- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 21773-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21773-1-AP, RRID:AB_10733242
- Product name
- ZO-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZO-1 antibody (Cat. #21773-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, Canine, mouse, rat, hamster and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Hamster
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice.
Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide-induced downregulation of zona occludens -1 expression via toll-like receptor 2/4-mediated c-Jun N-terminal kinase/activator protein-1 signalling pathways.
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.
Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device.
Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites.
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice.
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis.
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells.
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice.
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration.
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice.
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Brain endothelial LRP1 maintains blood-brain barrier integrity.
Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
CD151 Alleviates Early Blood-Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats.
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice.
A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics.
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Polystyrene microplastics induced male reproductive toxicity in mice.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.
Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.
First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation.
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis.
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Neutrophil extracellular traps induce a hypercoagulable state in glioma.
Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9.
Poly(ADP-ribose) polymerase inhibitor PJ34 protects against UVA-induced oxidative damage in corneal endothelium.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model.
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress.
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Multiple roles of FGF10 in the regulation of corneal endothelial wound healing.
Effects of the extract from peanut meal fermented with Bacillus natto and Monascus on lipid metabolism and intestinal barrier function of hyperlipidemic mice.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations.
Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease.
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells.
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κ
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strains in Reducing the Translocation of Staphylococcus aureus in the Caco-2 Monolayer Model.
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids.
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice.
Bioinformatics analysis of LINC01554 and its co‑expressed genes in hepatocellular carcinoma.
Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
Anthocyanins decrease the internalization of TiO2 nanoparticles into 3D Caco-2 spheroids.
Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.
Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage.
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Exposure to nonylphenol in early life increases pro-inflammatory cytokines in the prefrontal cortex: Involvement of gut-brain communication.
Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
CD147 Promoted Epithelial Mesenchymal Transition in Airway Epithelial Cells Induced by Cigarette Smoke via Oxidative Stress Signaling Pathway.
ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease.
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury.
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis.
Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Melatonin protects the mouse testis against heat-induced damage.
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier.
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1.
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Polysaccharide from the seeds of Plantago asiatica L. alleviates nonylphenol induced intestinal barrier injury by regulating tight junctions in human Caco-2 cell line.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Salvianolic acid B protects against myocardial ischaemia-reperfusion injury in rats via inhibiting high mobility group box 1 protein expression through the PI3K/Akt signalling pathway.
A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis.
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Metformin therapy confers cardioprotection against the remodeling of gap junction in tachycardia-induced atrial fibrillation dog model.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis.
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis.
Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1.
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro.
The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases.
An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Chitosan coating of zein-carboxymethylated short-chain amylose nanocomposites improves oral bioavailability of insulin in vitro and in vivo.
TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Epidermal growth factor treatment has protective effects on the integrity of the blood-brain barrier against cerebral ischemia injury in bEnd3 cells.
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Ethyl pyruvate protects against Salmonella intestinal infection in mice through down-regulation of pro-inflammatory factors and inhibition of TLR4/MAPK pathway.
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis.
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system.
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation.
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice.
Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice.
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells.
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy.
Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Butyrate Protects Mice Against Methionine-Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases.
Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer.
ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling.
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states.
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood-Brain Barrier Permeability During Early Reperfusion in Stroke.
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition.
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Tail Vein Infusion of Adipose-Derived Mesenchymal Stem Cell Alleviated Inflammatory Response and Improved Blood Brain Barrier Condition by Suppressing Endoplasmic Reticulum Stress in a Middle Cerebral Artery Occlusion Rat Model.
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells.
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.
Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense.
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Calycosin Suppresses Epithelial Derived Initiative Key Factors and Maintains Epithelial Barrier in Allergic Inflammation via TLR4 Mediated NF-κB Pathway.
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Role of macrophage migration inhibitory factor (MIF) in the effects of oxidative stress on human retinal pigment epithelial cells.
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats.
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Targeted deletion of Aqp4 promotes the formation of astrocytic gap junctions.
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability.
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Knockout of BRD7 results in impaired spermatogenesis and male infertility.
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model.
Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.
Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion.
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Li R, Chen C, Liu B, Shi W, Shimizu K, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153814
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153814
Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
Zhang D, Man X, Li L, Tang J, Liu F
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide-induced downregulation of zona occludens -1 expression via toll-like receptor 2/4-mediated c-Jun N-terminal kinase/activator protein-1 signalling pathways.
Liu L, Li Y, He Y, Wang Z, Zhao H, Jin X, Shi D, Wang X
Journal of applied microbiology 2022 Jan;132(1):605-617
Journal of applied microbiology 2022 Jan;132(1):605-617
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Gong L, Xiao J, Yi J, Xiao J, Lu F, Liu X
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.
Wei H, Zhen L, Wang S, Zhang Y, Wang K, Jia P, Zhang Y, Wu Z, Yang Q, Hou W, Lv J, Zhang P
Neuroscience 2022 Jan 15;481:85-98
Neuroscience 2022 Jan 15;481:85-98
Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device.
Tung YC, Wang CK, Huang YK, Huang CK, Peng CC, Patra B, Chen HK, Tsao PN, Ling TY
Talanta 2022 Jan 1;236:122882
Talanta 2022 Jan 1;236:122882
Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.
Huang T, Zhou Y, Lu X, Tang C, Ren C, Bao X, Deng Z, Cao X, Zou J, Zhang Q, Ma B
Andrologia 2022 Feb;54(1):e14294
Andrologia 2022 Feb;54(1):e14294
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
Wang S, Kai L, Zhu L, Xu B, Chen N, Valencak TG, Wang Y, Shan T
Frontiers in cell and developmental biology 2021;9:685363
Frontiers in cell and developmental biology 2021;9:685363
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.
Li Y, Tao Y, Xu J, He Y, Zhang W, Jiang Z, He Y, Liu H, Chen M, Zhang W, Xing Z
Frontiers in medicine 2021;8:732039
Frontiers in medicine 2021;8:732039
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites.
Wang S, Zhou J, Xiao D, Shu G, Gu L
Frontiers in nutrition 2021;8:660598
Frontiers in nutrition 2021;8:660598
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Wang D, Zhou L, Zhou H, Hou G
Frontiers in veterinary science 2021;8:656179
Frontiers in veterinary science 2021;8:656179
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.
Tian X, Cao H, Wu L, Zheng W, Yuan M, Li X, Song H, Shen Z
Stem cells international 2021;2021:9935370
Stem cells international 2021;2021:9935370
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Zou W, Qian C, Zhang S, Wan X, Wei Z, Li X, Wu Y, Chen W, Wang A, Zhao Y, Lu Y
Oxidative medicine and cellular longevity 2021;2021:7037786
Oxidative medicine and cellular longevity 2021;2021:7037786
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice.
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, Duan Z
Oxidative medicine and cellular longevity 2021;2021:6620873
Oxidative medicine and cellular longevity 2021;2021:6620873
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Wan Y, Song M, Xie X, Chen Z, Gao Z, Wu X, Huang R, Chen M
Mediators of inflammation 2021;2021:5522291
Mediators of inflammation 2021;2021:5522291
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Ren J, Yan D, Wang Y, Zhang J, Li M, Xiong W, Jing X, Li P, Zhao W, Xiong X, Wu M, Zhong G
Frontiers in immunology 2021;12:760999
Frontiers in immunology 2021;12:760999
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
Qu Y, Li X, Xu F, Zhao S, Wu X, Wang Y, Xie J
Frontiers in immunology 2021;12:679897
Frontiers in immunology 2021;12:679897
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
He Y, Chen J, Zhang Q, Zhang J, Wang L, Chen X, Molenaar AJ, Sun X
Frontiers in plant science 2021;12:673774
Frontiers in plant science 2021;12:673774
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Ye R, Wang C, Sun P, Bai S, Zhao L
Frontiers in pharmacology 2021;12:669403
Frontiers in pharmacology 2021;12:669403
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Chen L, Zhong X, Cao W, Mao M, Li W, Yang H, Li M, Shi M, Zhang Y, Deng Y, Zu X, Liu J
Frontiers in immunology 2021;12:609319
Frontiers in immunology 2021;12:609319
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Chen C, Yuan W, Zhou Q, Shao B, Guo Y, Wang W, Yang S, Guo Y, Zhao L, Dang Q, Yang X, Wang G, Kang Q, Ji Z, Liu J, Sun Z
Theranostics 2021;11(9):4298-4315
Theranostics 2021;11(9):4298-4315
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Qin Q, Chen Y, Li Y, Wei J, Zhou X, Le F, Hu H, Chen T
Frontiers in cellular and infection microbiology 2021;11:719542
Frontiers in cellular and infection microbiology 2021;11:719542
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Chen G, Yang Z, Wen D, Guo J, Xiong Q, Li P, Zhao L, Wang J, Wu C, Dong L
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis.
Zhang S, Guo M, Liu Q, Liu J, Cui Y
Immunity, inflammation and disease 2021 Sep;9(3):1025-1036
Immunity, inflammation and disease 2021 Sep;9(3):1025-1036
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901
Toxicology 2021 Sep;461:152901
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells.
Hinman SS, Huling J, Wang Y, Wang H, Bretherton RC, DeForest CA, Allbritton NL
Biomaterials 2021 Sep;276:121059
Biomaterials 2021 Sep;276:121059
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.
Zhang CL, Wang HL, Li PC, Hong CD, Chen AQ, Qiu YM, Zeng AP, Zhou YF, Hu B, Li YN
Pharmacological research 2021 Sep;171:105755
Pharmacological research 2021 Sep;171:105755
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Kuang H, Wang T, Liu L, Tang C, Li T, Liu M, Wang T, Zhong W, Wang Y
Neuroscience letters 2021 Sep 25;762:136134
Neuroscience letters 2021 Sep 25;762:136134
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
Xun W, Fu Q, Shi L, Cao T, Jiang H, Ma Z
International immunopharmacology 2021 Oct;99:107989
International immunopharmacology 2021 Oct;99:107989
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Zhong G, Zhang J, Guo Y, Wang Y, Wu M, Ren J, Li Y, Zhang X, Zhou B, Zhao W, Lou Y, Wang H, Ye J
International immunopharmacology 2021 Oct;99:107980
International immunopharmacology 2021 Oct;99:107980
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.
Lesko AC, Keller R, Chen P, Sutherland A
Developmental biology 2021 Oct;478:59-75
Developmental biology 2021 Oct;478:59-75
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Yu W, Jin H, Sun W, Nan D, Deng J, Jia J, Yu Z, Huang Y
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Xu SY, Bian HJ, Shu S, Xia SN, Gu Y, Zhang MJ, Xu Y, Cao X
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Li L, Cheng SQ, Guo W, Cai ZY, Sun YQ, Huang XX, Yang J, Ji J, Chen YY, Dong YF, Cheng H, Sun XL
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.
Xin J, Ma X, Chen W, Zhou W, Dong H, Wang Z, Ji F
Neurochemistry international 2021 Oct;149:105093
Neurochemistry international 2021 Oct;149:105093
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034
Cell death & disease 2021 Oct 30;12(11):1034
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Mikami R, Arisaka Y, Hakariya M, Iwata T, Yui N
Biomaterials science 2021 Oct 26;9(21):7151-7158
Biomaterials science 2021 Oct 26;9(21):7151-7158
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Du K, Li S, Li C, Li P, Miao C, Luo T, Qiu B, Ding W
Acta biomaterialia 2021 Oct 15;134:228-239
Acta biomaterialia 2021 Oct 15;134:228-239
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Lu YW, Hao RJ, Wei YY, Yu GR
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Zhu H, Lu C, Gao F, Qian Z, Yin Y, Kan S, Chen D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells.
Guo X, Chen J, Yang J, He Q, Luo B, Lu Y, Zou T, Wang Z, You J
Journal of animal physiology and animal nutrition 2021 Nov;105(6):1063-1074
Journal of animal physiology and animal nutrition 2021 Nov;105(6):1063-1074
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.
Wu T, Wang X, Xiong H, Deng Z, Peng X, Xiao L, Jiang L, Sun Y
Food & function 2021 Nov 29;12(23):11760-11776
Food & function 2021 Nov 29;12(23):11760-11776
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2021 Nov 29;
Oncogene 2021 Nov 29;
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.
Han D, Li F, Zhang H, Ji C, Shu Q, Wang C, Ni H, Zhu Y, Wang S
Journal of drug targeting 2021 Nov 18;:1-12
Journal of drug targeting 2021 Nov 18;:1-12
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Mu J, Que Y, Li X, Zhou F, Jin L, Li S, Zhu C
Vascular pharmacology 2021 Nov 13;142:106941
Vascular pharmacology 2021 Nov 13;142:106941
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.
Guo F, Tsao R, Li C, Wang X, Zhang H, Jiang L, Sun Y, Xiong H
Foods (Basel, Switzerland) 2021 Nov 11;10(11)
Foods (Basel, Switzerland) 2021 Nov 11;10(11)
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice.
Liu Y, Li Z, Khan S, Zhang R, Wei R, Zhang Y, Xue M, Yong VW
Neuroscience letters 2021 Nov 1;764:136297
Neuroscience letters 2021 Nov 1;764:136297
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Kong L, Ma Y, Wang Z, Liu N, Ma G, Liu C, Shi R, Du G
International immunopharmacology 2021 May;94:107507
International immunopharmacology 2021 May;94:107507
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Wang G, Hu YX, He MY, Xie YH, Su W, Long D, Zhao R, Wang J, Dai C, Li H, Si ZP, Cheng X, Li RM, Li Z, Yang X
The American journal of pathology 2021 May;191(5):838-856
The American journal of pathology 2021 May;191(5):838-856
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research.
Sun JK, Zhou J, Sun XP, Shen X, Zhu DM, Wang X, Zhou SM, Mu XW
Journal of intensive care 2021 May 3;9(1):37
Journal of intensive care 2021 May 3;9(1):37
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;
CNS neuroscience & therapeutics 2021 May 13;
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Xue S, Tang H, Zhao G, Fang C, Shen Y, Yan D, Yuan Y, Fu W, Shi Z, Tang X, Guo D
Free radical biology & medicine 2021 May 1;167:181-192
Free radical biology & medicine 2021 May 1;167:181-192
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Li L, Zhou C, Li T, Xiao W, Yu M, Yang H
Annals of translational medicine 2021 Mar;9(5):365
Annals of translational medicine 2021 Mar;9(5):365
Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration.
Niu X, Sang H, Wang J
The Journal of nutritional biochemistry 2021 Mar;89:108560
The Journal of nutritional biochemistry 2021 Mar;89:108560
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
Liu CD, Liu NN, Zhang S, Ma GD, Yang HG, Kong LL, Du GH
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
Wang Y, Sun J, Xue L, Liu J, Nie C, Fan M, Qian H, Zhang D, Ying H, Li Y, Wang L
Journal of agricultural and food chemistry 2021 Mar 31;69(12):3638-3646
Journal of agricultural and food chemistry 2021 Mar 31;69(12):3638-3646
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Zhu S, Liang J, Zhu F, Zhang X, Xu M, Zhao K, Zeng L, Xu K
Bioscience reports 2021 Mar 26;41(3)
Bioscience reports 2021 Mar 26;41(3)
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Wang W, Zhai D, Bai Y, Xue K, Deng L, Ma L, Du T, Ye Z, Qu D, Xiang A, Chen G, Zhao Y, Wang L, Lu Z
Cell death discovery 2021 Mar 23;7(1):58
Cell death discovery 2021 Mar 23;7(1):58
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice.
Esposito G, Pesce M, Seguella L, Lu J, Corpetti C, Del Re A, De Palma FDE, Esposito G, Sanseverino W, Sarnelli G
International journal of molecular sciences 2021 Mar 14;22(6)
International journal of molecular sciences 2021 Mar 14;22(6)
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Zou T, Yang J, Guo X, He Q, Wang Z, You J
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Zhang Z, Zhang Q, Li F, Xin Y, Duan Z
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Eilenberger C, Rothbauer M, Selinger F, Gerhartl A, Jordan C, Harasek M, Schädl B, Grillari J, Weghuber J, Neuhaus W, Küpcü S, Ertl P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jun;8(11):e2004856
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jun;8(11):e2004856
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Shu Y, Huang J, Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Xu D, Gao Q, Wang F, Peng Q, Wang G, Wei Q, Lei S, Zhao S, Zhang L, Guo F
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Sun XH, Xiao HM, Zhang M, Lin ZY, Yang Y, Chen R, Liu PQ, Huang KP, Huang HQ
Biochemical pharmacology 2021 Jun;188:114562
Biochemical pharmacology 2021 Jun;188:114562
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Zhuang M, Deng Y, Zhang W, Zhu B, Yan H, Lou J, Zhang P, Cui Q, Tang H, Sun H, Sun Y
Cell death & disease 2021 Jun 9;12(6):595
Cell death & disease 2021 Jun 9;12(6):595
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Lu L, Lu T, Shen J, Lv X, Wei W, Wang H, Xue X
Aging 2021 Jun 4;13(11):15353-15365
Aging 2021 Jun 4;13(11):15353-15365
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Yan X, Ren X, Liu X, Wang Y, Ma J, Song R, Wang X, Dong Y, Fan Q, Wei J, Yu A, She G
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Brain endothelial LRP1 maintains blood-brain barrier integrity.
Storck SE, Kurtyka M, Pietrzik CU
Fluids and barriers of the CNS 2021 Jun 19;18(1):27
Fluids and barriers of the CNS 2021 Jun 19;18(1):27
Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.
Dutton JS, Hinman SS, Kim R, Attayek PJ, Maurer M, Sims CS, Allbritton NL
Integrative biology : quantitative biosciences from nano to macro 2021 Jun 15;13(6):139-152
Integrative biology : quantitative biosciences from nano to macro 2021 Jun 15;13(6):139-152
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Chen Y, Zhang H, Chen Y, Jia P, Ji S, Zhang Y, Wang T
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Liu FY, Wen J, Hou J, Zhang SQ, Sun CB, Zhou LC, Yin W, Pang WL, Wang C, Ying Y, Han SS, Yan JY, Li CX, Yuan JL, Xing HJ, Yang ZS
International immunopharmacology 2021 Jul;96:107758
International immunopharmacology 2021 Jul;96:107758
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Liu N, Liu C, Yang Y, Ma G, Wei G, Liu S, Kong L, Du G
Pharmacological research 2021 Jul;169:105650
Pharmacological research 2021 Jul;169:105650
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Wang Y, Guan X, Gao CL, Ruan W, Zhao S, Kai G, Li F, Pang T
Pharmacological research 2021 Jul;169:105640
Pharmacological research 2021 Jul;169:105640
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Gao C, Xu Y, Liang Z, Wang Y, Shang Q, Zhang S, Wang C, Ni M, Wu D, Huang Z, Pang T
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Zong X, Cheng Y, Xiao X, Fu J, Wang F, Lu Z, Wang Y, Jin M
International journal of biological macromolecules 2021 Jul 31;183:861-869
International journal of biological macromolecules 2021 Jul 31;183:861-869
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
Yang R, Shen YJ, Chen M, Zhao JY, Chen SH, Zhang W, Song JK, Li L, Du GH
Journal of Asian natural products research 2021 Jul 22;:1-12
Journal of Asian natural products research 2021 Jul 22;:1-12
Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.
Jin Z, Chen K, Zhou Z, Peng W, Liu W
Scientific reports 2021 Jul 21;11(1):14894
Scientific reports 2021 Jul 21;11(1):14894
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Fu J, Li L, Huo D, Yang R, Yang B, Xu B, Yang X, Dai M, Tan C, Chen H, Wang X
Molecular brain 2021 Jul 19;14(1):116
Molecular brain 2021 Jul 19;14(1):116
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Fang M, Wan W, Li Q, Wan W, Long Y, Liu H, Yang X
Life sciences 2021 Jul 15;277:119567
Life sciences 2021 Jul 15;277:119567
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Li HL, Wei YY, Li XH, Zhang SS, Zhang RT, Li JH, Ma BW, Shao SB, Lv ZW, Ruan H, Zhou HG, Yang C
Acta pharmacologica Sinica 2021 Jul 14;
Acta pharmacologica Sinica 2021 Jul 14;
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
Cao YY, Wang ZH, Xu QC, Chen Q, Wang Z, Lu WH
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Jul 1;25(4):375-383
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Jul 1;25(4):375-383
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Cao YY, Wang Z, Wang ZH, Jiang XG, Lu WH
International immunopharmacology 2021 Jan;90:107218
International immunopharmacology 2021 Jan;90:107218
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
Hu XQ, Tang Y, Ju Y, Zhang XY, Yan JJ, Wang CM, Yang Y, Zhu C, Tang ZX, Zhou Y, Yu G
Clinical and experimental dermatology 2021 Jan;46(1):74-81
Clinical and experimental dermatology 2021 Jan;46(1):74-81
CD151 Alleviates Early Blood-Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats.
Xu W, Gao C, Wu J
Cellular and molecular neurobiology 2021 Jan;41(1):151-162
Cellular and molecular neurobiology 2021 Jan;41(1):151-162
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Jia Z, Bao K, Wei P, Yu X, Zhang Y, Wang X, Wang X, Yao L, Li L, Wu P, Yuan W, Wang S, Zheng J, Hua Y, Hong M
Mucosal immunology 2021 Jan;14(1):125-134
Mucosal immunology 2021 Jan;14(1):125-134
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice.
Wu H, Chen QY, Wang WZ, Chu S, Liu XX, Liu YJ, Tan C, Zhu F, Deng SJ, Dong YL, Yu T, Gao F, He HX, Leng XY, Fan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110937
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110937
A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics.
Wright L, Joyce P, Barnes TJ, Lundmark R, Bergström CAS, Hubert M, Prestidge CA
Journal of pharmaceutical sciences 2021 Jan;110(1):217-227
Journal of pharmaceutical sciences 2021 Jan;110(1):217-227
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Fu J, Li L, Huo D, Zhi S, Yang R, Yang B, Xu B, Zhang T, Dai M, Tan C, Chen H, Wang X
Brain sciences 2021 Jan 8;11(1)
Brain sciences 2021 Jan 8;11(1)
Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
Jiang K, Chen H, Fang Y, Chen L, Zhong C, Bu T, Dai S, Pan X, Fu D, Qian Y, Wei J, Ding K
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):21
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):21
Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.
Niu X, Shang H, Chen S, Chen R, Huang J, Miao Y, Cui W, Wang H, Sha Z, Peng D, Zhu R
Food & function 2021 Jan 7;12(1):252-266
Food & function 2021 Jan 7;12(1):252-266
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Chi H, Cao W, Zhang M, Su D, Yang H, Li Z, Li C, She X, Wang K, Gao X, Ma K, Zheng P, Li X, Cui B
Journal of neuroinflammation 2021 Jan 6;18(1):9
Journal of neuroinflammation 2021 Jan 6;18(1):9
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Toan NK, Tai NC, Kim SA, Ahn SG
International journal of molecular sciences 2021 Jan 2;22(1)
International journal of molecular sciences 2021 Jan 2;22(1)
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Zong X, Xiao X, Kai L, Cheng Y, Fu J, Xu W, Wang Y, Zhao K, Jin M
International journal of biological macromolecules 2021 Jan 15;167:76-84
International journal of biological macromolecules 2021 Jan 15;167:76-84
Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.
Sun N, Hu H, Wang F, Li L, Zhu W, Shen Y, Xiu J, Xu Q
Brain, behavior, and immunity 2021 Feb;92:102-114
Brain, behavior, and immunity 2021 Feb;92:102-114
Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.
Liu H, Zhan Q, Miao X, Xia X, Yang G, Peng X, Yan C
Molecular nutrition & food research 2021 Feb;65(4):e2001031
Molecular nutrition & food research 2021 Feb;65(4):e2001031
First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Citraro R, Lembo F, De Caro C, Tallarico M, Coretti L, Iannone LF, Leo A, Palumbo D, Cuomo M, Buommino E, Nesci V, Marascio N, Iannone M, Quirino A, Russo R, Calignano A, Constanti A, Russo E, De Sarro G
Epilepsia 2021 Feb;62(2):529-541
Epilepsia 2021 Feb;62(2):529-541
Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation.
Xie X, Zhang L, Yuan S, Li H, Zheng C, Xie S, Sun Y, Zhang C, Wang R, Jin Y
Journal of cellular and molecular medicine 2021 Feb;25(3):1439-1455
Journal of cellular and molecular medicine 2021 Feb;25(3):1439-1455
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis.
Chen J, Chen R, Huang S, Zu B, Zhang S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Ma J, Shah AM, Wang ZS, Hu R, Zou HW, Wang XY, Zhao SN, Kong XY
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Chen KJ, Chen YL, Ueng SH, Hwang TL, Kuo LM, Hsieh PW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Veenstra JP, Vemu B, Tocmo R, Nauman MC, Johnson JJ
Nutrients 2021 Feb 27;13(3)
Nutrients 2021 Feb 27;13(3)
Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.
Li S, Zheng M, Zhang Z, Peng H, Dai W, Liu J
Chinese medicine 2021 Feb 16;16(1):22
Chinese medicine 2021 Feb 16;16(1):22
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Li J, Zhang L, Wu T, Li Y, Zhou X, Ruan Z
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Neutrophil extracellular traps induce a hypercoagulable state in glioma.
Zhang S, Guo M, Liu Q, Liu J, Cui Y
Immunity, inflammation and disease 2021 Dec;9(4):1383-1393
Immunity, inflammation and disease 2021 Dec;9(4):1383-1393
Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9.
Zhang H, Dong W, Li S, Zhang Y, Lv Z, Yang L, Jiang L, Wu T, Wang Y
Pharmaceutical biology 2021 Dec;59(1):760-768
Pharmaceutical biology 2021 Dec;59(1):760-768
Poly(ADP-ribose) polymerase inhibitor PJ34 protects against UVA-induced oxidative damage in corneal endothelium.
Wang X, Dong C, Zhou Q, Duan H, Zou D, Gong Y, Ma B, Li Z, Shi W
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):600-611
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):600-611
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model.
Mendonça MCP, Cronin MF, Cryan JF, O'Driscoll CM
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021 Dec;169:309-318
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021 Dec;169:309-318
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X
Virulence 2021 Dec;12(1):2296-2313
Virulence 2021 Dec;12(1):2296-2313
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Fan X, Xia Q, Zhang Y, Li Y, Feng Z, Zhou J, Qi J, Tang BZ, Qian J, Lin H
Advanced healthcare materials 2021 Dec;10(24):e2101043
Advanced healthcare materials 2021 Dec;10(24):e2101043
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Xie X, Zhou J, Hu L, Shu R, Zhang M, Xiong Z, Wu F, Fu Z
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.
Chen Z, Wu Y, Wang B, Fang J, Gan C, Sang C, Dun Z, Luosang T, Wang Q, Zeren D, Xiong T
Environmental toxicology and pharmacology 2021 Aug;86:103672
Environmental toxicology and pharmacology 2021 Aug;86:103672
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Peng C, Wang Y, Ji L, Kuang L, Yu Z, Li H, Zhang J, Zhao J
Current eye research 2021 Aug;46(8):1137-1147
Current eye research 2021 Aug;46(8):1137-1147
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Nie Y, Hui L, Guo M, Yang W, Huang R, Chen J, Wen X, Zhao M, Wu Y
Virologica Sinica 2021 Aug;36(4):692-705
Virologica Sinica 2021 Aug;36(4):692-705
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849
Cancer gene therapy 2021 Aug;28(7-8):839-849
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Bai X, Fu R, Duan Z, Wang P, Zhu C, Fan D
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
Liu C, Hua H, Zhu H, Cheng Y, Guo Y, Yao W, Qian H
International journal of biological macromolecules 2021 Aug 31;185:804-812
International journal of biological macromolecules 2021 Aug 31;185:804-812
Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress.
Liu WC, Zhu YR, Zhao ZH, Jiang P, Yin FQ
Animals : an open access journal from MDPI 2021 Aug 2;11(8)
Animals : an open access journal from MDPI 2021 Aug 2;11(8)
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Gao R, Tian S, Wang J, Zhu W
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Jiao-Yan Y, Qing-Qing L, Xi L, Mei Z, Ting S, Na H, Wei J, Rui-Tao Z, Peng Y, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Chen Y, Jiang Z, Lei Z, Ping J, Su J
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Chang Y, Deng Q, Zhang Z, Zhao H, Tang J, Chen X, Liu G, Tian G, Cai J, Jia G
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Yan M, Wang H, Gu Y, Li X, Tao L, Lu P
Experimental eye research 2021 Apr;205:108521
Experimental eye research 2021 Apr;205:108521
Multiple roles of FGF10 in the regulation of corneal endothelial wound healing.
Wang X, Zhou Q, Zhao C, Duan H, Li W, Dong C, Gong Y, Li Z, Shi W
Experimental eye research 2021 Apr;205:108517
Experimental eye research 2021 Apr;205:108517
Effects of the extract from peanut meal fermented with Bacillus natto and Monascus on lipid metabolism and intestinal barrier function of hyperlipidemic mice.
Lu Y, Ding H, Jiang X, Zhang H, Ma A, Hu Y, Li Z
Journal of the science of food and agriculture 2021 Apr;101(6):2561-2569
Journal of the science of food and agriculture 2021 Apr;101(6):2561-2569
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations.
Chang SH, Ko PL, Liao WH, Peng CC, Tung YC
Micromachines 2021 Apr 6;12(4)
Micromachines 2021 Apr 6;12(4)
Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease.
Altomare A, Gori M, Cocca S, Carotti S, Francesconi M, Ribolsi M, Emerenziani S, Perrone G, Morini S, Cicala M, Guarino MPL
Journal of neurogastroenterology and motility 2021 Apr 30;27(2):292-301
Journal of neurogastroenterology and motility 2021 Apr 30;27(2):292-301
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells.
Lin Y, Zhang C, Xiang P, Shen J, Sun W, Yu H
Journal of extracellular vesicles 2020;9(1):1722385
Journal of extracellular vesicles 2020;9(1):1722385
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.
Liu X, Chen Y, You B, Peng Y, Chen Y, Yang Z, Zhang Y, Chen J
Burns & trauma 2020;8:tkaa042
Burns & trauma 2020;8:tkaa042
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Ma J, Shah AM, Wang Z, Hu R, Zou H, Wang X, Cao G, Peng Q, Xue B, Wang L, Zhao S, Kong X
PeerJ 2020;8:e9851
PeerJ 2020;8:e9851
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.
Nettleford SK, Zhao L, Qian F, Herold M, Arner B, Desai D, Amin S, Xiong N, Singh V, Carlson BA, Prabhu KS
Frontiers in nutrition 2020;7:96
Frontiers in nutrition 2020;7:96
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Yang H, Cai R, Kong Z, Chen Y, Cheng C, Qi S, Gu B
Frontiers in medicine 2020;7:584369
Frontiers in medicine 2020;7:584369
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Liu DY, Lou WJ, Zhang DY, Sun SY
BioMed research international 2020;2020:8819195
BioMed research international 2020;2020:8819195
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Li C, Wang X, Yan J, Cheng F, Ma X, Chen C, Wang W, Wang Q
Oxidative medicine and cellular longevity 2020;2020:1201624
Oxidative medicine and cellular longevity 2020;2020:1201624
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Xie J, Hong E, Ding B, Jiang W, Zheng S, Xie Z, Tian D, Chen Y
Frontiers in cellular neuroscience 2020;14:578060
Frontiers in cellular neuroscience 2020;14:578060
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Zou X, Wang Y, Wang Y, Yang J, Guo H, Cai Z
Drug design, development and therapy 2020;14:5623-5632
Drug design, development and therapy 2020;14:5623-5632
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Li B, Zhou X, Yi TL, Xu ZW, Peng DW, Guo Y, Guo YM, Cao YL, Zhu L, Zhang S, Cheng SX
Frontiers in neuroscience 2020;14:403
Frontiers in neuroscience 2020;14:403
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Zhong M, Zhu M, Liu Y, Lin Y, Wang L, Ye Y, Chen H, Yang Y, Zhuang G, Huang J
Journal of Cancer 2020;11(10):3061-3071
Journal of Cancer 2020;11(10):3061-3071
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Hu R, He Z, Liu M, Tan J, Zhang H, Hou DX, He J, Wu S
Journal of animal science and biotechnology 2020;11:92
Journal of animal science and biotechnology 2020;11:92
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Yang K, Liu J, Zhang X, Ren Z, Gao L, Wang Y, Lin W, Ma X, Hao M, Kuang H
Frontiers in pharmacology 2020;11:603689
Frontiers in pharmacology 2020;11:603689
Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strains in Reducing the Translocation of Staphylococcus aureus in the Caco-2 Monolayer Model.
Peng Z, Wei B, Huang T, Liu Z, Guan Q, Xie M, Li H, Xiong T
Frontiers in microbiology 2020;11:566473
Frontiers in microbiology 2020;11:566473
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Zhang H, Chen Y, Chen Y, Ji S, Jia P, Li Y, Wang T
Journal of animal science and biotechnology 2020;11:52
Journal of animal science and biotechnology 2020;11:52
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Wen C, Guo Q, Wang W, Duan Y, Zhang L, Li J, He S, Chen W, Li F
Frontiers in physiology 2020;11:449
Frontiers in physiology 2020;11:449
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
He S, Guo Y, Zhao J, Xu X, Wang N, Liu Q
Frontiers in pharmacology 2020;11:376
Frontiers in pharmacology 2020;11:376
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Ding F, Wu J, Liu C, Bian Q, Qiu W, Ma Q, Li X, Long M, Zou X, Chen J
Frontiers in pharmacology 2020;11:1069
Frontiers in pharmacology 2020;11:1069
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Lv W, Graves DT, He L, Shi Y, Deng X, Zhao Y, Dong X, Ren Y, Liu X, Xiao E, Zhang Y
Theranostics 2020;10(14):6500-6516
Theranostics 2020;10(14):6500-6516
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Yang T, Heydarian M, Kozjak-Pavlovic V, Urban M, Harbottle RP, Rudel T
Frontiers in cellular and infection microbiology 2020;10:422
Frontiers in cellular and infection microbiology 2020;10:422
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901
Molecular neurobiology 2020 Sep;57(9):3891-3901
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)
Marine drugs 2020 Sep 29;18(10)
Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids.
Yoshimoto S, Yoshizumi J, Anzai H, Morishita K, Okamura K, Hiraki A, Hashimoto S
Disease models & mechanisms 2020 Sep 28;13(9)
Disease models & mechanisms 2020 Sep 28;13(9)
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Furutama D, Matsuda S, Yamawaki Y, Hatano S, Okanobu A, Memida T, Oue H, Fujita T, Ouhara K, Kajiya M, Mizuno N, Kanematsu T, Tsuga K, Kurihara H
Brain sciences 2020 Sep 27;10(10)
Brain sciences 2020 Sep 27;10(10)
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Yang Q, Luo L, Sun T, Yang L, Cheng LF, Wang Y, Liu QQ, Liu A, Liu HY, Zhao MG, Wu SX, Feng B
Psychopharmacology 2020 Oct;237(10):3201-3213
Psychopharmacology 2020 Oct;237(10):3201-3213
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Sondorp LHJ, Ogundipe VML, Groen AH, Kelder W, Kemper A, Links TP, Coppes RP, Kruijff S
Cancers 2020 Oct 31;12(11)
Cancers 2020 Oct 31;12(11)
Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice.
Li L, Li R, Zhu R, Chen B, Tian Y, Zhang H, Xia B, Jia Q, Wang L, Zhao D, Mo F, Li Y, Zhang S, Gao S, Zhang D, Guo S
Food & function 2020 Oct 21;11(10):8743-8756
Food & function 2020 Oct 21;11(10):8743-8756
Bioinformatics analysis of LINC01554 and its co‑expressed genes in hepatocellular carcinoma.
Li L, Huang K, Lu Z, Zhao H, Li H, Ye Q, Peng G
Oncology reports 2020 Nov;44(5):2185-2197
Oncology reports 2020 Nov;44(5):2185-2197
Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
Yang L, Bian X, Wu W, Lv L, Li Y, Ye J, Jiang X, Wang Q, Shi D, Fang D, Wu J, Wang K, Wang Q, Xia J, Xie J, Lu Y, Li L
Microbial biotechnology 2020 Nov;13(6):1860-1876
Microbial biotechnology 2020 Nov;13(6):1860-1876
Anthocyanins decrease the internalization of TiO2 nanoparticles into 3D Caco-2 spheroids.
Wang J, Zhang J, Li S, Huang C, Xie Y, Cao Y
Food chemistry 2020 Nov 30;331:127360
Food chemistry 2020 Nov 30;331:127360
Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.
Jiang Z, Mu W, Yang Y, Sun M, Liu Y, Gao Z, Li J, Gu P, Wang H, Lu Y, Ba Q, Wang H
The Science of the total environment 2020 Nov 20;744:140844
The Science of the total environment 2020 Nov 20;744:140844
Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.
Li S, Ma B, Wang J, Peng H, Zheng M, Dai W, Liu J
Journal of agricultural and food chemistry 2020 Nov 19;
Journal of agricultural and food chemistry 2020 Nov 19;
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Xiao Q, Shu R, Wu C, Tong Y, Xiong Z, Zhou J, Yu C, Xie X, Fu Z
Journal of affective disorders 2020 Nov 1;276:476-486
Journal of affective disorders 2020 Nov 1;276:476-486
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.
Jia Y, Cui R, Wang C, Feng Y, Li Z, Tong Y, Qu K, Liu C, Zhang J
Redox biology 2020 May;32:101534
Redox biology 2020 May;32:101534
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage.
Wang C, Cao J, Duan S, Xu R, Yu H, Huo X, Qian Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May;29(5):104748
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May;29(5):104748
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Wu N, Wu Z, Sun J, Yan M, Wang B, Du X, Liu Y
Aging 2020 May 5;12(9):7927-7944
Aging 2020 May 5;12(9):7927-7944
Exposure to nonylphenol in early life increases pro-inflammatory cytokines in the prefrontal cortex: Involvement of gut-brain communication.
Che X, Fang Y, You M, Xu Y, Wang Y
Chemico-biological interactions 2020 May 25;323:109076
Chemico-biological interactions 2020 May 25;323:109076
Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro.
Gori M, Altomare A, Cocca S, Solida E, Ribolsi M, Carotti S, Rainer A, Francesconi M, Morini S, Cicala M, Guarino MPL
Antioxidants (Basel, Switzerland) 2020 May 13;9(5)
Antioxidants (Basel, Switzerland) 2020 May 13;9(5)
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773
Cell proliferation 2020 Mar;53(3):e12773
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Huang M, Wang Q, Long F, Di Y, Wang J, Zhun Zhu Y, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Li H, Fan C, Lu H, Feng C, He P, Yang X, Xiang C, Zuo J, Tang W
Acta pharmaceutica Sinica. B 2020 Mar;10(3):447-461
Acta pharmaceutica Sinica. B 2020 Mar;10(3):447-461
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
Liu S, Dai Y, Zhou C, Zhu T
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Liang H, Yu M, Yang R, Zhang L, Zhang L, Zhu D, Luo H, Hong Y, Yu T, Sun J, Shan H, Gu Y
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.
Su H, Zhang C, Zou X, Lu F, Zeng Y, Guan H, Ren Y, Yuan F, Xu L, Zhang M, Dong H
Journal of ethnopharmacology 2020 Mar 25;250:112478
Journal of ethnopharmacology 2020 Mar 25;250:112478
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.
Shen S, Zhao J, Dai Y, Chen F, Zhang Z, Yu J, Wang K
Toxicology letters 2020 Mar 15;321:73-82
Toxicology letters 2020 Mar 15;321:73-82
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Yin J, Zhou C, Yang K, Ren Y, Qiu Y, Xu P, Xiao W, Yang H
Cell biology international 2020 Jun;44(6):1405-1414
Cell biology international 2020 Jun;44(6):1405-1414
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
Wu Y, Wu B, Zhang Z, Lu H, Fan C, Qi Q, Gao Y, Li H, Feng C, Zuo J, Tang W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8028-8043
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8028-8043
CD147 Promoted Epithelial Mesenchymal Transition in Airway Epithelial Cells Induced by Cigarette Smoke via Oxidative Stress Signaling Pathway.
Zhou H, Liu Y, Wang Z, Yang Y, Li M, Yuan D, Zhang X, Li Y
COPD 2020 Jun;17(3):269-279
COPD 2020 Jun;17(3):269-279
ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.
Shimizu A, Goh WH, Itai S, Hashimoto M, Miura S, Onoe H
Lab on a chip 2020 Jun 2;20(11):1917-1927
Lab on a chip 2020 Jun 2;20(11):1917-1927
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
Thounaojam MC, Jadeja RN, Rajpurohit S, Gutsaeva DR, Stansfield BK, Martin PM, Bartoli M
Journal of clinical medicine 2020 Jun 19;9(6)
Journal of clinical medicine 2020 Jun 19;9(6)
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease.
Uemasu K, Tanabe N, Tanimura K, Hasegawa K, Mizutani T, Hamakawa Y, Sato S, Ogawa E, Thomas MJ, Ikegami M, Muro S, Hirai T, Sato A
American journal of respiratory cell and molecular biology 2020 Jul;63(1):67-78
American journal of respiratory cell and molecular biology 2020 Jul;63(1):67-78
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Cui L, Gu Y, Liu S, Li M, Ye J, Zhang F, Luo X, Chang WL, Gui Y
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1443-1454
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1443-1454
Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury.
Gao C, Wang H, Wang T, Luo C, Wang Z, Zhang M, Chen X, Tao L
Journal of neurochemistry 2020 Jul;154(2):190-204
Journal of neurochemistry 2020 Jul;154(2):190-204
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Sun X, Huang K, Haiming X, Lin Z, Yang Y, Zhang M, Liu P, Huang H
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Bai R, Sun D, Chen M, Shi X, Luo L, Yao Z, Liu Y, Ge X, Gao X, Hu GF, Zhou W, Sheng J, Xu Z
The EMBO journal 2020 Jul 1;39(13):e103325
The EMBO journal 2020 Jul 1;39(13):e103325
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Zhu C, Zhao L, Zhao J, Zhang S
International journal of molecular medicine 2020 Jan;45(1):53-60
International journal of molecular medicine 2020 Jan;45(1):53-60
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Guo F, Xu D, Lin Y, Wang G, Wang F, Gao Q, Wei Q, Lei S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis.
Dai FF, Bao AY, Luo B, Zeng ZH, Pu XL, Wang YQ, Zhang L, Xian S, Yuan MQ, Yang DY, Liu SY, Cheng YX
Experimental and therapeutic medicine 2020 Jan;19(1):264-272
Experimental and therapeutic medicine 2020 Jan;19(1):264-272
Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α.
Liu P, Bian Y, Fan Y, Zhong J, Liu Z
Journal of agricultural and food chemistry 2020 Jan 8;68(1):168-175
Journal of agricultural and food chemistry 2020 Jan 8;68(1):168-175
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Lu Z, Zhang D, Cui K, Fu X, Man J, Lu H, Yu L, Gao Y, Liu X, Liao L, Li X, Liu C, Zhang Y, Zhang Z, Wang J
Neuroscience 2020 Jan 21;428:228-241
Neuroscience 2020 Jan 21;428:228-241
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Melatonin protects the mouse testis against heat-induced damage.
Zhang P, Zheng Y, Lv Y, Li F, Su L, Qin Y, Zeng W
Molecular human reproduction 2020 Feb 29;26(2):65-79
Molecular human reproduction 2020 Feb 29;26(2):65-79
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Liu Y, Zhang S, Li X, Liu E, Wang X, Zhou Q, Ye J, Wang JZ
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier.
Wu S, Liu H, Zhao H, Wang X, Chen J, Xia D, Xiao C, Cheng J, Zhao Z, He Y
Toxicology letters 2020 Feb 1;319:138-147
Toxicology letters 2020 Feb 1;319:138-147
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Wang S, Chen Q, Zhang Y, Zheng F, Xue T, Ge X, Ma R, Li X, Wu R, Liang K, Qian Z, Ge Y, Ma J, Yao B
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:233-241
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:233-241
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
Khazoom F, L'Écuyer S, Gilbert K, Gagné MA, Bouchard C, Rose CF, Rousseau G, Charbonney E
The journal of trauma and acute care surgery 2020 Dec;89(6):1076-1084
The journal of trauma and acute care surgery 2020 Dec;89(6):1076-1084
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Hu Q, Lan J, Liang W, Chen Y, Chen B, Liu Z, Xiong Y, Zhong Z, Wang Y, Ye Q
Journal of molecular histology 2020 Dec;51(6):685-700
Journal of molecular histology 2020 Dec;51(6):685-700
Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1.
Liu MB, Wang W, Gao JM, Li F, Shi JS, Gong QH
Acta pharmacologica Sinica 2020 Dec;41(12):1547-1556
Acta pharmacologica Sinica 2020 Dec;41(12):1547-1556
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Zhu H, Xiao X, Shi Y, Wu Y, Huang Y, Li D, Xiong F, He G, Chai Y, Tang H
Experimental and therapeutic medicine 2020 Dec;20(6):155
Experimental and therapeutic medicine 2020 Dec;20(6):155
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Chen Q, Wang Y, Jiao F, Shi C, Pei M, Wang L, Gong Z
Scientific reports 2020 Dec 14;10(1):21850
Scientific reports 2020 Dec 14;10(1):21850
Polysaccharide from the seeds of Plantago asiatica L. alleviates nonylphenol induced intestinal barrier injury by regulating tight junctions in human Caco-2 cell line.
Li F, Du P, Yang W, Huang D, Nie S, Xie M
International journal of biological macromolecules 2020 Dec 1;164:2134-2140
International journal of biological macromolecules 2020 Dec 1;164:2134-2140
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Zhou YQ, Liu DQ, Chen SP, Chen N, Sun J, Wang XM, Cao F, Tian YK, Ye DW
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Salvianolic acid B protects against myocardial ischaemia-reperfusion injury in rats via inhibiting high mobility group box 1 protein expression through the PI3K/Akt signalling pathway.
Liu H, Liu W, Qiu H, Zou D, Cai H, Chen Q, Zheng C, Xu D
Naunyn-Schmiedeberg's archives of pharmacology 2020 Aug;393(8):1527-1539
Naunyn-Schmiedeberg's archives of pharmacology 2020 Aug;393(8):1527-1539
A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis.
Wu G, Wei W, Zhang J, Nie W, Yuan L, Huang Y, Zuo L, Huang L, Xi X, Xie HY
Biomaterials 2020 Aug;250:119963
Biomaterials 2020 Aug;250:119963
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Cong LH, Li T, Wang H, Wu YN, Wang SP, Zhao YY, Zhang GQ, Duan J
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)
Brain sciences 2020 Aug 8;10(8)
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Tan J, Liu H, Huang M, Li N, Tang S, Meng J, Tang S, Zhou H, Kijlstra A, Yang P, Hou S
Cell death & disease 2020 Aug 22;11(8):697
Cell death & disease 2020 Aug 22;11(8):697
Metformin therapy confers cardioprotection against the remodeling of gap junction in tachycardia-induced atrial fibrillation dog model.
Li J, Li B, Bai F, Ma Y, Liu N, Liu Y, Wang Y, Liu Q
Life sciences 2020 Aug 1;254:117759
Life sciences 2020 Aug 1;254:117759
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Li P, Wu M, Xiong W, Li J, An Y, Ren J, Xie Y, Xue H, Yan D, Li M, Zhong G
International immunopharmacology 2020 Apr;81:106288
International immunopharmacology 2020 Apr;81:106288
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Zhou J, Xi Y, Zhang J, Tang J, Zhou X, Chen J, Nie C, Zhu Z, Ma B
Andrologia 2020 Apr;52(3):e13508
Andrologia 2020 Apr;52(3):e13508
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Bai L, Liang J, Li L, Li E
Oncology reports 2020 Apr;43(4):1208-1220
Oncology reports 2020 Apr;43(4):1208-1220
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Li X, Yao Z, Yang D, Jiang X, Sun J, Tian L, Hu J, Wu B, Bai W
Journal of hazardous materials 2020 Apr 5;387:121706
Journal of hazardous materials 2020 Apr 5;387:121706
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
He J, Jiang YL, Wang Y, Tian XJ, Sun SR
Chinese medical journal 2020 Apr 5;133(7):800-807
Chinese medical journal 2020 Apr 5;133(7):800-807
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Li H, Feng C, Fan C, Yang Y, Yang X, Lu H, Lu Q, Zhu F, Xiang C, Zhang Z, He P, Zuo J, Tang W
Cell death & disease 2020 Apr 24;11(4):271
Cell death & disease 2020 Apr 24;11(4):271
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Li M, Liu G, Wang K, Wang L, Fu X, Lim LY, Chen W, Mo J
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cheng Y, Wu T, Tang S, Liang F, Fang Y, Cao W, Pan S, Xu X
Food & function 2020 Apr 1;11(4):3167-3179
Food & function 2020 Apr 1;11(4):3167-3179
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Wang Y, Kim R, Sims CE, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2019;8(4):653-655.e5
Cellular and molecular gastroenterology and hepatology 2019;8(4):653-655.e5
Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Li D, Yuan D, Shen H, Mao X, Yuan S, Liu Q
Molecular vision 2019;25:625-635
Molecular vision 2019;25:625-635
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Guo Y, Huang C, Liu L, Fu X, Lu Y, Zheng J, Mei Q, Huang Z, Fan J, Lu L, Zeng Y
Mediators of inflammation 2019;2019:8474523
Mediators of inflammation 2019;2019:8474523
Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Zhuang Y, Wu H, Wang X, He J, He S, Yin Y
Oxidative medicine and cellular longevity 2019;2019:7591840
Oxidative medicine and cellular longevity 2019;2019:7591840
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis.
Yan Z, Yang F, Hong Z, Wang S, Jinjuan Z, Han B, Xie R, Leng F, Yang Q
Canadian journal of gastroenterology & hepatology 2019;2019:5236149
Canadian journal of gastroenterology & hepatology 2019;2019:5236149
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.
Su YR, Hong YP, Mei FC, Wang CY, Li M, Zhou Y, Zhao KL, Yu J, Wang WX
Mediators of inflammation 2019;2019:2512687
Mediators of inflammation 2019;2019:2512687
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Speer JE, Gunasekara DB, Wang Y, Fallon JK, Attayek PJ, Smith PC, Sims CE, Allbritton NL
Journal of biological engineering 2019;13:36
Journal of biological engineering 2019;13:36
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
Hu L, Wu C, Zhang Z, Liu M, Maruthi Prasad E, Chen Y, Wang K
Frontiers in physiology 2019;10:908
Frontiers in physiology 2019;10:908
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis.
Guo W, Liu B, Yin Y, Kan X, Gong Q, Li Y, Cao Y, Wang J, Xu D, Ma H, Fu S, Liu J
Frontiers in immunology 2019;10:287
Frontiers in immunology 2019;10:287
Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Bian X, Wu W, Yang L, Lv L, Wang Q, Li Y, Ye J, Fang D, Wu J, Jiang X, Shi D, Li L
Frontiers in microbiology 2019;10:2259
Frontiers in microbiology 2019;10:2259
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Pavlovic V
Frontiers in microbiology 2019;10:1740
Frontiers in microbiology 2019;10:1740
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Bao K, Yuan W, Zhou Y, Chen Y, Yu X, Wang X, Jia Z, Yu X, Wang X, Yao L, Wang S, Xu Y, Zhang Y, Zheng J, Hong M
Frontiers in pharmacology 2019;10:1698
Frontiers in pharmacology 2019;10:1698
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674
Frontiers in immunology 2019;10:1674
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1.
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM
Frontiers in physiology 2019;10:134
Frontiers in physiology 2019;10:134
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Martins Gomes SF, Westermann AJ, Sauerwein T, Hertlein T, Förstner KU, Ohlsen K, Metzger M, Shusta EV, Kim BJ, Appelt-Menzel A, Schubert-Unkmeir A
Frontiers in microbiology 2019;10:1181
Frontiers in microbiology 2019;10:1181
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Luo L, Liu Y, Cai X, Wang Y, Xue J, Zhang J, Yang F
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Li X, Mao M, Zhang Y, Yu K, Zhu W
Biomolecules 2019 Sep 13;9(9)
Biomolecules 2019 Sep 13;9(9)
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ, Zhu JY, Xie CF, Li XT, Zhong CY, Han HY
The Journal of nutritional biochemistry 2019 Oct;72:108219
The Journal of nutritional biochemistry 2019 Oct;72:108219
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Lan XB, Wang Q, Yang JM, Ma L, Zhang WJ, Zheng P, Sun T, Niu JG, Liu N, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, Xu Y, Zhang J, Shao C
Scientific reports 2019 Oct 23;9(1):15221
Scientific reports 2019 Oct 23;9(1):15221
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro.
Li CX, Wang XQ, Cheng FF, Yan X, Luo J, Wang QG
Neural regeneration research 2019 Nov;14(11):1941-1949
Neural regeneration research 2019 Nov;14(11):1941-1949
The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases.
Li X, Wang F, Ren M, Du M, Zhou J
BMC ophthalmology 2019 Nov 8;19(1):219
BMC ophthalmology 2019 Nov 8;19(1):219
An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface.
Kim R, Attayek PJ, Wang Y, Furtado KL, Tamayo R, Sims CE, Allbritton NL
Biofabrication 2019 Nov 6;12(1):015006
Biofabrication 2019 Nov 6;12(1):015006
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Chitosan coating of zein-carboxymethylated short-chain amylose nanocomposites improves oral bioavailability of insulin in vitro and in vivo.
Ji N, Hong Y, Gu Z, Cheng L, Li Z, Li C
Journal of controlled release : official journal of the Controlled Release Society 2019 Nov 10;313:1-13
Journal of controlled release : official journal of the Controlled Release Society 2019 Nov 10;313:1-13
TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Han S, Zhou H, Cai L, Li J, Liu N, Liu Y, Wang L, Fan C, Li A, Miao Y
Molecular carcinogenesis 2019 May;58(5):767-776
Molecular carcinogenesis 2019 May;58(5):767-776
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Yin M, Shen Z, Yang L, Zheng W, Song H
International journal of molecular medicine 2019 May;43(5):2086-2102
International journal of molecular medicine 2019 May;43(5):2086-2102
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
Fu C, Hao S, Xu X, Zhou J, Liu Z, Lu H, Wang L, Jin W, Li S
Acta pharmacologica Sinica 2019 May;40(5):630-641
Acta pharmacologica Sinica 2019 May;40(5):630-641
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Feng Z, Wang JW, Wang Y, Dong WW, Xu ZF
Medical science monitor : international medical journal of experimental and clinical research 2019 May 1;25:3199-3211
Medical science monitor : international medical journal of experimental and clinical research 2019 May 1;25:3199-3211
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Zhou F, Jiang Z, Yang B, Hu Z
Brain, behavior, and immunity 2019 Mar;77:161-167
Brain, behavior, and immunity 2019 Mar;77:161-167
Epidermal growth factor treatment has protective effects on the integrity of the blood-brain barrier against cerebral ischemia injury in bEnd3 cells.
Yang S, Jin H, Zhao ZG
Experimental and therapeutic medicine 2019 Mar;17(3):2397-2402
Experimental and therapeutic medicine 2019 Mar;17(3):2397-2402
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Liu M, Li Y, Liu Y, Yan S, Liu G, Zhang Q, Ji B
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Liu X, Dong H, Huang B, Miao H, Xu Z, Yuan Y, Qiu F, Chen J, Zhang H, Liu Z, Quan X, Zhu L, Zhang Z
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Ethyl pyruvate protects against Salmonella intestinal infection in mice through down-regulation of pro-inflammatory factors and inhibition of TLR4/MAPK pathway.
Dong N, Xu X, Xue C, Wang C, Li X, Shan A, Xu L, Li D
International immunopharmacology 2019 Jun;71:155-163
International immunopharmacology 2019 Jun;71:155-163
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
Adegoke EO, Adeniran SO, Zeng Y, Wang X, Wang H, Wang C, Zhang H, Zheng P, Zhang G
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.
Zhu D, Zhou J, Zhao J, Jiang G, Zhang X, Zhang Y, Dong M
Journal of cellular physiology 2019 Jun;234(6):8899-8907
Journal of cellular physiology 2019 Jun;234(6):8899-8907
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Scheiber IF, Wu Y, Morgan SE, Zhao N
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Wang XM, Li QY, Ren LL, Liu YM, Wang TS, Mu TC, Fu S, Liu C, Xiao JY
Cellular signalling 2019 Jul;59:171-181
Cellular signalling 2019 Jul;59:171-181
Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis.
Yang Y, Yan X, Xue J, Zheng Y, Chen M, Sun Z, Liu T, Wang C, You H, Luo D
Cell death and differentiation 2019 Jul;26(7):1332-1345
Cell death and differentiation 2019 Jul;26(7):1332-1345
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
Li H, Fan C, Feng C, Wu Y, Lu H, He P, Yang X, Zhu F, Qi Q, Gao Y, Zuo J, Tang W
British journal of pharmacology 2019 Jul;176(13):2209-2226
British journal of pharmacology 2019 Jul;176(13):2209-2226
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Sun S, Cai B, Li Y, Su W, Zhao X, Gong B, Li Z, Zhang X, Wu Y, Chen C, Tsang SH, Yang J, Li X
Aging 2019 Jul 7;11(13):4323-4337
Aging 2019 Jul 7;11(13):4323-4337
Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system.
Li C, Wang X, Cheng F, Du X, Yan J, Zhai C, Mu J, Wang Q
European journal of pharmacology 2019 Jul 5;854:224-231
European journal of pharmacology 2019 Jul 5;854:224-231
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Zhang M, Zhao J, Deng J, Duan Z, Zhu C, Fan D
Food & function 2019 Jul 17;10(7):4124-4133
Food & function 2019 Jul 17;10(7):4124-4133
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Yuan W, Ji J, Shu Y, Chen J, Liu S, Wu L, Zhou Z, Liu Z, Tang Q, Zhang X, Shu X
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Liu Z, Chen J, Yuan W, Ruan H, Shu Y, Ji J, Wu L, Tang Q, Zhou Z, Zhang X, Cheng Y, He S, Shu X
Cancer science 2019 Jan;110(1):86-98
Cancer science 2019 Jan;110(1):86-98
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Wang J, Tian S, Yu H, Wang J, Zhu W
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
Wang J, Yu M, Xu J, Cheng Y, Li X, Wei G, Wang H, Kong H, Xie W
Journal of biomedical science 2019 Jan 12;26(1):6
Journal of biomedical science 2019 Jan 12;26(1):6
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
Zhai J, Geng X, Ding T, Li J, Tang J, Chen D, Cui L, Wang Q
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Li J, Hao Y, Mao W, Xue X, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z, Luo J, Chen R, Zhao RC
Journal of hematology & oncology 2019 Feb 22;12(1):19
Journal of hematology & oncology 2019 Feb 22;12(1):19
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice.
Guo W, Liu B, Hu G, Kan X, Li Y, Gong Q, Xu D, Ma H, Cao Y, Huang B, Fu S, Liu J
Toxicology and applied pharmacology 2019 Feb 15;365:9-18
Toxicology and applied pharmacology 2019 Feb 15;365:9-18
Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.
Jia M, Yan X, Jiang X, Wu Y, Xu J, Meng Y, Yang Y, Shan X, Zhang X, Mao S, Gu W, Pavlidis S, Barnes PJ, Adcock IM, Huang M, Yao X
American journal of respiratory and critical care medicine 2019 Feb 15;199(4):496-507
American journal of respiratory and critical care medicine 2019 Feb 15;199(4):496-507
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Chai S, Liu K, Feng W, Liu T, Wang Q, Zhou R, Chen S, Wang L, Chen G, Ming T, Zhao J, Liu C, Xue B
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
Wang X, Zou Y, Li Y, Chen Z, Yin C, Wang Y, Zhang L, Wu J, Yang C, Zhang G, Zou Y, Gong H
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Wu M, Li P, An Y, Ren J, Yan D, Cui J, Li D, Li M, Wang M, Zhong G
Pharmacological research 2019 Dec;150:104489
Pharmacological research 2019 Dec;150:104489
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
Li XX, Ling SK, Hu MY, Ma Y, Li Y, Huang PL
Free radical biology & medicine 2019 Dec;145:175-186
Free radical biology & medicine 2019 Dec;145:175-186
The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
Terao R, Honjo M, Totsuka K, Miwa Y, Kurihara T, Aihara M
Prostaglandins & other lipid mediators 2019 Dec;145:106365
Prostaglandins & other lipid mediators 2019 Dec;145:106365
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
You M, Miao Z, Pan Y, Hu F
European journal of pharmacology 2019 Dec 15;865:172736
European journal of pharmacology 2019 Dec 15;865:172736
Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice.
Song L, Xie W, Liu Z, Guo D, Zhao D, Qiao X, Wang L, Zhou H, Cui W, Jiang Y, Li Y, Xu Y, Tang L
Applied microbiology and biotechnology 2019 Aug;103(15):6169-6186
Applied microbiology and biotechnology 2019 Aug;103(15):6169-6186
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Sun L, Zhang W, Li Z, Li M, Guo J, Wang H, Wang X
Scientific reports 2019 Aug 8;9(1):11510
Scientific reports 2019 Aug 8;9(1):11510
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Zhu X, Ye Y, Xu C, Gao C, Zhang Y, Zhou J, Lin W, Mao J
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells.
Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV
Fluids and barriers of the CNS 2019 Aug 22;16(1):26
Fluids and barriers of the CNS 2019 Aug 22;16(1):26
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy.
Song P, Li Y, Dong Y, Liang Y, Qu H, Qi D, Lu Y, Jin X, Guo Y, Jia Y, Wang X, Xu W, Quan C
Journal of experimental & clinical cancer research : CR 2019 Aug 14;38(1):354
Journal of experimental & clinical cancer research : CR 2019 Aug 14;38(1):354
Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.
Frost TS, Jiang L, Lynch RM, Zohar Y
Micromachines 2019 Aug 13;10(8)
Micromachines 2019 Aug 13;10(8)
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Xu J, Wei G, Wang J, Zhu J, Yu M, Zeng X, Wang H, Xie W, Kong H
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, Wu X, Yang Z, Tian L, Wang X
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Li X, Dong M, Zhou J, Zhu D, Zhao J, Sheng W
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Butyrate Protects Mice Against Methionine-Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels.
Ye J, Lv L, Wu W, Li Y, Shi D, Fang D, Guo F, Jiang H, Yan R, Ye W, Li L
Frontiers in microbiology 2018;9:1967
Frontiers in microbiology 2018;9:1967
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Wang Y, Kim R, Gunasekara DB, Reed MI, DiSalvo M, Nguyen DL, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Zhou X, Zhang Y, Wu X, Wan D, Yin Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):993-1002
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):993-1002
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Wang Y, Chen H, Chen Q, Jiao FZ, Zhang WB, Gong ZJ
Mediators of inflammation 2018;2018:7859601
Mediators of inflammation 2018;2018:7859601
Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases.
Chen X, Liu R, Liu X, Xu C, Wang X
BioMed research international 2018;2018:7207268
BioMed research international 2018;2018:7207268
Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.
Lu S, Zhang T, Gu W, Yang X, Lu J, Zhao R, Yu J
BioMed research international 2018;2018:3589874
BioMed research international 2018;2018:3589874
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, Chen G, Li X, Xiao W, Xu P, Yang H
International journal of biological sciences 2018;14(1):69-77
International journal of biological sciences 2018;14(1):69-77
A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer.
Xu K, Liu B, Ma Y, Xu B, Xing X
Cancer management and research 2018;10:3245-3254
Cancer management and research 2018;10:3245-3254
ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling.
Liu B, Xing X, Li X, Guo Q, Xu T, Xu K
Cancer management and research 2018;10:3159-3168
Cancer management and research 2018;10:3159-3168
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Ma J, Yin G, Lu Z, Xie P, Zhou H, Liu J, Yu L
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, Hong M
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Luo L, Zhou Z, Xue J, Wang Y, Zhang J, Cai X, Liu Y, Yang F
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Wang W, Hu Y, Yang C, Zhu S, Wang X, Zhang Z, Deng H
Molecular & cellular proteomics : MCP 2018 Oct;17(10):2005-2017
Molecular & cellular proteomics : MCP 2018 Oct;17(10):2005-2017
Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.
He X, Sun Z, Manthari RK, Wu P, Wang J
Chemosphere 2018 Nov;211:826-833
Chemosphere 2018 Nov;211:826-833
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Wu YY, Li TM, Zang LQ, Liu B, Wang GX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Yan M, Yang X, Shen R, Wu C, Wang H, Ye Q, Yang P, Zhang L, Chen M, Wan B, Zhang Q, Xia S, Lu X, Shao G, Zhou X, Yu J, Shao Q
Cell death & disease 2018 Nov 8;9(11):1123
Cell death & disease 2018 Nov 8;9(11):1123
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Yang Y, Dong B, Lu J, Wang G, Yu Y
Brain research 2018 Nov 15;1699:177-185
Brain research 2018 Nov 15;1699:177-185
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
Zhu L, Yang N, Du G, Li C, Liu G, Liu S, Xu Y, Di Y, Pan W, Li X
Journal of cellular biochemistry 2018 Nov 14;
Journal of cellular biochemistry 2018 Nov 14;
Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states.
Wu Y, Ding ZY, Jin GN, Xiong YX, Yu B, Sun YM, Wang W, Liang HF, Zhang B, Chen XP
Biochimie 2018 May;148:87-98
Biochimie 2018 May;148:87-98
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Wang X, Zhang X, Hu L, Li H
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Yu M, Chen Y, Li X, Yang R, Zhang L, Huangfu L, Zheng N, Zhao X, Lv L, Hong Y, Liang H, Shan H
Cell death & disease 2018 May 1;9(5):464
Cell death & disease 2018 May 1;9(5):464
Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood-Brain Barrier Permeability During Early Reperfusion in Stroke.
Zhang S, An Q, Wang T, Gao S, Zhou G
Neuroscience 2018 May 1;377:126-137
Neuroscience 2018 May 1;377:126-137
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, Sheng B, Li X, Sun L, Yu M, Yang H
International journal of molecular medicine 2018 Mar;41(3):1560-1572
International journal of molecular medicine 2018 Mar;41(3):1560-1572
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
Zhang X, Jiang G, Wu J, Zhou H, Zhang Y, Miao Y, Feng Y, Yu J
Oncology letters 2018 Mar;15(3):3806-3813
Oncology letters 2018 Mar;15(3):3806-3813
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition.
Wang W, Hu Y, Wang X, Wang Q, Deng H
Cell chemical biology 2018 Mar 15;25(3):255-261.e4
Cell chemical biology 2018 Mar 15;25(3):255-261.e4
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.
Liu L, Yao J, Li Z, Zu G, Feng D, Li Y, Qasim W, Zhang S, Li T, Zeng H, Tian X
Cell death & disease 2018 Mar 14;9(3):411
Cell death & disease 2018 Mar 14;9(3):411
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Zhang Z, Zhang L, Chen J, Cao Y, Qu M, Lin X, Han Z, Ji X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Cui B, Su D, Li W, She X, Zhang M, Wang R, Zhai Q
Journal of neuroinflammation 2018 Jun 22;15(1):190
Journal of neuroinflammation 2018 Jun 22;15(1):190
Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis.
Ye JZ, Li YT, Wu WR, Shi D, Fang DQ, Yang LY, Bian XY, Wu JJ, Wang Q, Jiang XW, Peng CG, Ye WC, Xia PC, Li LJ
World journal of gastroenterology 2018 Jun 21;24(23):2468-2481
World journal of gastroenterology 2018 Jun 21;24(23):2468-2481
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
Tail Vein Infusion of Adipose-Derived Mesenchymal Stem Cell Alleviated Inflammatory Response and Improved Blood Brain Barrier Condition by Suppressing Endoplasmic Reticulum Stress in a Middle Cerebral Artery Occlusion Rat Model.
Chi L, Huang Y, Mao Y, Wu K, Zhang L, Nan G
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 11;24:3946-3957
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 11;24:3946-3957
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
Zeng J, Zhào H, Liu Z, Zhang W, Huang Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Liu M, Yang J, Zhang Y, Zhou Z, Cui X, Zhang L, Fung KM, Zheng W, Allard FD, Yee EU, Ding K, Wu H, Liang Z, Zheng L, Fernandez-Zapico ME, Li YP, Bronze MS, Morris KT, Postier RG, Houchen CW, Yang J, Li M
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Yang S, Jin H, Zhao Z
Neurological research 2018 Feb;40(2):117-121
Neurological research 2018 Feb;40(2):117-121
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
Tian H, Xu JY, Tian Y, Cao Y, Lian C, Ou Q, Wu B, Jin C, Gao F, Wang J, Zhang J, Zhang J, Li W, Lu L, Xu GT
Experimental eye research 2018 Dec;177:160-172
Experimental eye research 2018 Dec;177:160-172
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Wang S, Xie T, Sun S, Wang K, Liu B, Wu X, Ding W
Scientific reports 2018 Dec 12;8(1):17788
Scientific reports 2018 Dec 12;8(1):17788
Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells.
Yang S, Jin H, Zhao Z
Neurological research 2018 Aug;40(8):644-649
Neurological research 2018 Aug;40(8):644-649
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.
Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP
Molecular neurodegeneration 2018 Apr 4;13(1):17
Molecular neurodegeneration 2018 Apr 4;13(1):17
Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.
Lee WC, Su CH, Tain YL, Tsai CN, Yu CC, Chuang YC
Scientific reports 2018 Apr 11;8(1):5795
Scientific reports 2018 Apr 11;8(1):5795
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Zhang T, Lu SH, Bi Q, Liang L, Wang YF, Yang XX, Gu W, Yu J
Frontiers in pharmacology 2017;8:786
Frontiers in pharmacology 2017;8:786
Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense.
Zeng Q, He X, Puthiyakunnon S, Xiao H, Gong Z, Boddu S, Chen L, Tian H, Huang SH, Cao H
Frontiers in microbiology 2017;8:1798
Frontiers in microbiology 2017;8:1798
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Li L, Wang N, Jin Q, Wu Q, Liu Y, Wang Y
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Calycosin Suppresses Epithelial Derived Initiative Key Factors and Maintains Epithelial Barrier in Allergic Inflammation via TLR4 Mediated NF-κB Pathway.
Tao Y, Wang Y, Wang X, Wang C, Bao K, Ji L, Jiang G, Hong M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(3):1106-1119
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(3):1106-1119
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Yang S, Mei S, Jin H, Zhu B, Tian Y, Huo J, Cui X, Guo A, Zhao Z
PloS one 2017;12(10):e0187017
PloS one 2017;12(10):e0187017
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Li W, Li X, Liu S, Yang W, Pan F, Yang XY, Du B, Qin L, Pan Y
International journal of nanomedicine 2017;12:3509-3520
International journal of nanomedicine 2017;12:3509-3520
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Zhang X, Zhou H, Cai L, Fan C, Liu Y, Wang L, Li Q, Miao Y
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Zhang X, Liu Y, Fan C, Wang L, Li A, Zhou H, Cai L, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Sep 26;8(43):75102-75113
Oncotarget 2017 Sep 26;8(43):75102-75113
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Zhang X, Zhang Y, Miao Y, Zhou H, Jiang G, Wang E
Oncotarget 2017 Sep 19;8(41):70685-70694
Oncotarget 2017 Sep 19;8(41):70685-70694
Role of macrophage migration inhibitory factor (MIF) in the effects of oxidative stress on human retinal pigment epithelial cells.
Ko JA, Sotani Y, Ibrahim DG, Kiuchi Y
Cell biochemistry and function 2017 Oct;35(7):426-432
Cell biochemistry and function 2017 Oct;35(7):426-432
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition.
Zhang L, Zhang Z, Liu B, Jin Y, Tian Y, Xin Y, Duan Z
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:215-224
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:215-224
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
He L, Zhou X, Huang N, Li H, Cui Z, Tian J, Jiang Q, Liu S, Wu J, Li T, Yao K, Yin Y
Oncotarget 2017 Nov 3;8(54):91965-91978
Oncotarget 2017 Nov 3;8(54):91965-91978
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Han J, Li JH, Bai G, Shen GS, Chen J, Liu JN, Wang S, Liu XJ
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Zhou H, Zhang Y, Cai L, Jiang G, Li A, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Jun 13;8(24):38863-38875
Oncotarget 2017 Jun 13;8(24):38863-38875
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Wang Y, DiSalvo M, Gunasekara DB, Dutton J, Proctor A, Lebhar MS, Williamson IA, Speer J, Howard RL, Smiddy NM, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Du J, Zhang X, Zhou H, Miao Y, Han Y, Han Q, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats.
Li Z, Chen X, Zhang X, Ren X, Chen X, Cao J, Zang W, Liu X, Guo F
Journal of molecular neuroscience : MN 2017 Feb;61(2):279-288
Journal of molecular neuroscience : MN 2017 Feb;61(2):279-288
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, Wang E, Zhang Y
Oncotarget 2017 Feb 21;8(8):13357-13366
Oncotarget 2017 Feb 21;8(8):13357-13366
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Zhang X, Cai L, Zhou H, Liu Y, Fan C, Wang L, Li A, Miao Y, Li Q, Qiu X, Wang E
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Targeted deletion of Aqp4 promotes the formation of astrocytic gap junctions.
Katoozi S, Skauli N, Rahmani S, Camassa LMA, Boldt HB, Ottersen OP, Amiry-Moghaddam M
Brain structure & function 2017 Dec;222(9):3959-3972
Brain structure & function 2017 Dec;222(9):3959-3972
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
Appelt-Menzel A, Cubukova A, Günther K, Edenhofer F, Piontek J, Krause G, Stüber T, Walles H, Neuhaus W, Metzger M
Stem cell reports 2017 Apr 11;8(4):894-906
Stem cell reports 2017 Apr 11;8(4):894-906
CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
Ramena G, Yin Y, Yu Y, Walia V, Elble RC
PloS one 2016;11(3):e0147489
PloS one 2016;11(3):e0147489
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Yang R, Liu W, Miao L, Yang X, Fu J, Dou B, Cai A, Zong X, Tan C, Chen H, Wang X
Oncotarget 2016 Sep 27;7(39):63839-63855
Oncotarget 2016 Sep 27;7(39):63839-63855
Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability.
Huang C, Wen B
Molecular biology reports 2016 Oct;43(10):1069-78
Molecular biology reports 2016 Oct;43(10):1069-78
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
Kong J, Luo Y, Jin D, An F, Zhang W, Liu L, Li J, Fang S, Li X, Yang X, Lin B, Liu T
Oncotarget 2016 Nov 29;7(48):78421-78432
Oncotarget 2016 Nov 29;7(48):78421-78432
SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W
JCI insight 2016 Nov 17;1(19):e86934
JCI insight 2016 Nov 17;1(19):e86934
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Suzuki R, Nakamura Y, Chiba S, Mizuno T, Abe K, Horii Y, Nagashima H, Tanita T, Yamauchi K
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Knockout of BRD7 results in impaired spermatogenesis and male infertility.
Wang H, Zhao R, Guo C, Jiang S, Yang J, Xu Y, Liu Y, Fan L, Xiong W, Ma J, Peng S, Zeng Z, Zhou Y, Li X, Li Z, Li X, Schmitt DC, Tan M, Li G, Zhou M
Scientific reports 2016 Feb 16;6:21776
Scientific reports 2016 Feb 16;6:21776
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Wang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao J
Molecular neurobiology 2016 Dec;53(10):7298-7311
Molecular neurobiology 2016 Dec;53(10):7298-7311
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, Peng K, Wang W, Xiao W, Yang H
International journal of biological sciences 2015;11(6):664-71
International journal of biological sciences 2015;11(6):664-71
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
Lin P, Lu J, Wang Y, Gu W, Yu J, Zhao R
PloS one 2015;10(10):e0140346
PloS one 2015;10(10):e0140346
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Yu X, Zhang X, Zhang Y, Jiang G, Mao X, Jin F
Oncotarget 2015 Sep 22;6(28):25034-45
Oncotarget 2015 Sep 22;6(28):25034-45
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Dong WW, Liu YJ, Lv Z, Mao YF, Wang YW, Zhu XY, Jiang L
Free radical biology & medicine 2015 Nov;88(Pt B):404-416
Free radical biology & medicine 2015 Nov;88(Pt B):404-416
Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
Yu M, Yang S, Qiu Y, Chen G, Wang W, Xu C, Cai W, Sun L, Xiao W, Yang H
Journal of gastroenterology 2015 Nov;50(11):1103-13
Journal of gastroenterology 2015 Nov;50(11):1103-13
The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.
Zhou Y, Zhang Y, Zou H, Cai N, Chen X, Xu L, Kong X, Liu P
Scientific reports 2015 Feb 27;5:8629
Scientific reports 2015 Feb 27;5:8629
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Zhang X, Miao Y, Yu X, Zhang Y, Jiang G, Liu Y, Yu J, Han Q, Zhao H, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
Miao L, Xiong X, Lin Y, Cheng Y, Lu J, Zhang J, Cheng N
Oncology letters 2014 Mar;7(3):658-662
Oncology letters 2014 Mar;7(3):658-662
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ning Q, Liu C, Hou L, Meng M, Zhang X, Luo M, Shao S, Zuo X, Zhao X
PloS one 2013;8(6):e65217
PloS one 2013;8(6):e65217
Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model.
Cai Y, Wang W, Liang H, Sun L, Teitelbaum DH, Yang H
Scandinavian journal of gastroenterology 2013 Apr;48(4):419-26
Scandinavian journal of gastroenterology 2013 Apr;48(4):419-26
Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.
Juric M, Xiao F, Amasheh S, May O, Wahl K, Bantel H, Manns MP, Seidler U, Bachmann O
Inflammatory bowel diseases 2013 Apr;19(5):904-11
Inflammatory bowel diseases 2013 Apr;19(5):904-11
Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion.
Cai Y, Wang W, Liang H, Sun L, Teitelbaum DH, Yang H
PloS one 2012;7(9):e44772
PloS one 2012;7(9):e44772
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Eilert-Olsen M, Haj-Yasein NN, Vindedal GF, Enger R, Gundersen GA, Hoddevik EH, Petersen PH, Haug FM, Skare Ø, Adams ME, Froehner SC, Burkhardt JM, Thoren AE, Nagelhus EA
Glia 2012 Mar;60(3):432-40
Glia 2012 Mar;60(3):432-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 21773-1-AP(ZO1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21773-1-AP(ZO1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21773-1-AP(ZO1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZO-1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZO-1. This antibody recognizes human antigen. The ZO-1 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
