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Western blot
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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [15]
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- Validations
- Immunocytochemistry [3]
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- Product number
- ADI-SOD-100-F - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- Cu/Zn SOD polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Purified from natural sources
- Description
- Protein A affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 200 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Exposure of Female Rats to an Environmentally Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis.
Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions.
Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy.
A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.
Respiratory syncytial virus infection down-regulates antioxidant enzyme expression by triggering deacetylation-proteasomal degradation of Nrf2.
Versican localizes to the nucleus in proliferating mesenchymal cells.
The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues.
Changes of the Cytoplasmic Proteome in Response to Alcoholic Hepatotoxicity in Rats.
Sod1 loss induces intrinsic superoxide accumulation leading to p53-mediated growth arrest and apoptosis.
Huntingtin fragments and SOD1 mutants form soluble oligomers in the cell.
A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice.
Effect of exposure to benzo[a]pyrene on SODs, CYP1A1/1A2- and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis.
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity.
Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries.
Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis.
Lefèvre PL, Berger RG, Ernest SR, Gaertner DW, Rawn DF, Wade MG, Robaire B, Hales BF
Biology of reproduction 2016 Dec;94(1):9
Biology of reproduction 2016 Dec;94(1):9
Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions.
Collins JA, Moots RJ, Clegg PD, Milner PI
Free radical biology & medicine 2015 Sep;86:57-64
Free radical biology & medicine 2015 Sep;86:57-64
Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy.
Nakamae S, Kobatake Y, Suzuki R, Tsukui T, Kato S, Yamato O, Sakai H, Urushitani M, Maeda S, Kamishina H
Neuroscience 2015 Sep 10;303:229-40
Neuroscience 2015 Sep 10;303:229-40
A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.
Fujisawa T, Yamaguchi N, Kadowaki H, Tsukamoto Y, Tsuburaya N, Tsubota A, Takahashi H, Naguro I, Takahashi Y, Goto J, Tsuji S, Nishitoh H, Homma K, Ichijo H
Neurobiology of disease 2015 Oct;82:478-86
Neurobiology of disease 2015 Oct;82:478-86
Respiratory syncytial virus infection down-regulates antioxidant enzyme expression by triggering deacetylation-proteasomal degradation of Nrf2.
Komaravelli N, Tian B, Ivanciuc T, Mautemps N, Brasier AR, Garofalo RP, Casola A
Free radical biology & medicine 2015 Nov;88(Pt B):391-403
Free radical biology & medicine 2015 Nov;88(Pt B):391-403
Versican localizes to the nucleus in proliferating mesenchymal cells.
Carthy JM, Abraham T, Meredith AJ, Boroomand S, McManus BM
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2015 Nov-Dec;24(6):368-74
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2015 Nov-Dec;24(6):368-74
The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues.
Pate KM, Sherk VD, Carpenter RD, Weaver M, Crapo S, Gally F, Chatham LS, Goldstrohm DA, Crapo JD, Kohrt WM, Bowler RP, Oberley-Deegan RE, Regan EA
Journal of applied physiology (Bethesda, Md. : 1985) 2015 Mar 15;118(6):760-7
Journal of applied physiology (Bethesda, Md. : 1985) 2015 Mar 15;118(6):760-7
Changes of the Cytoplasmic Proteome in Response to Alcoholic Hepatotoxicity in Rats.
Kim DH, Lee EM, Do SH, Jeong DH, Jeong KS
International journal of molecular sciences 2015 Aug 10;16(8):18664-82
International journal of molecular sciences 2015 Aug 10;16(8):18664-82
Sod1 loss induces intrinsic superoxide accumulation leading to p53-mediated growth arrest and apoptosis.
Watanabe K, Shibuya S, Koyama H, Ozawa Y, Toda T, Yokote K, Shimizu T
International journal of molecular sciences 2013 May 24;14(6):10998-1010
International journal of molecular sciences 2013 May 24;14(6):10998-1010
Huntingtin fragments and SOD1 mutants form soluble oligomers in the cell.
Park YN, Zhao X, Norton M, Taylor JP, Eisenberg E, Greene LE
PloS one 2012;7(6):e40329
PloS one 2012;7(6):e40329
A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice.
Teuling E, van Dis V, Wulf PS, Haasdijk ED, Akhmanova A, Hoogenraad CC, Jaarsma D
Human molecular genetics 2008 Sep 15;17(18):2849-62
Human molecular genetics 2008 Sep 15;17(18):2849-62
Effect of exposure to benzo[a]pyrene on SODs, CYP1A1/1A2- and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis.
Monari M, Cattani O, Serrazanetti GP, Selli A, Pagliuca G, Zironi E, O'Hara SC, Livingstone DR
Marine environmental research 2007 Apr;63(3):200-18
Marine environmental research 2007 Apr;63(3):200-18
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity.
Niwa J, Ishigaki S, Hishikawa N, Yamamoto M, Doyu M, Murata S, Tanaka K, Taniguchi N, Sobue G
The Journal of biological chemistry 2002 Sep 27;277(39):36793-8
The Journal of biological chemistry 2002 Sep 27;277(39):36793-8
Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries.
Woodman CR, Price EM, Laughlin MH
Journal of applied physiology (Bethesda, Md. : 1985) 2002 Nov;93(5):1685-90
Journal of applied physiology (Bethesda, Md. : 1985) 2002 Nov;93(5):1685-90
Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis.
Shinder GA, Lacourse MC, Minotti S, Durham HD
The Journal of biological chemistry 2001 Apr 20;276(16):12791-6
The Journal of biological chemistry 2001 Apr 20;276(16):12791-6
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of Cu/Zn SOD, pAb (Prod. No. ADI-SOD-100): Lane 1: Rat liver tissue lysate, Lane 2: Mouse liver tissue lysate, Lane 3: HeLa cell lysate (Prod. No. ADI-LYC-HL100).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human heart tissue stained with Cu/Zn SOD, pAb at 10µg/ml.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunofluorescent analysis (confocal) staining of HeLa cells using Cu/Zn SOD pAb (green); nuclei are stained in blue pseudocolor using DRAQ5.
