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- References [7]
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- Product number
- 60084-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60084-1-Ig, RRID:AB_2090985
- Product name
- DGCR8 antibody
- Antibody type
- Monoclonal
- Description
- DGCR8 antibody (Cat. #60084-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4D11A3
- Vial size
- 20ul, 150ul
Submitted references Hypoxia regulates overall mRNA homeostasis by inducing Met1-linked linear ubiquitination of AGO2 in cancer cells.
p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease.
Global miRNA dosage control of embryonic germ layer specification.
DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Primary microRNA precursor transcripts are localized at post-synaptic densities in adult mouse forebrain.
Identification of microprocessor-dependent cancer cells allows screening for growth-sustaining micro-RNAs.
Zhang H, Zhao X, Guo Y, Chen R, He J, Li L, Qiang Z, Yang Q, Liu X, Huang C, Lu R, Fang J, Cao Y, Huang J, Wang Y, Huang J, Chen GQ, Cheng J, Yu J
Nature communications 2021 Sep 13;12(1):5416
Nature communications 2021 Sep 13;12(1):5416
p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease.
Xu H, Liu X, Li W, Xi Y, Su P, Meng B, Shao X, Tang B, Yang Q, Mao Z
Aging cell 2021 Oct;20(10):e13434
Aging cell 2021 Oct;20(10):e13434
Global miRNA dosage control of embryonic germ layer specification.
Cui Y, Lyu X, Ding L, Ke L, Yang D, Pirouz M, Qi Y, Ong J, Gao G, Du P, Gregory RI
Nature 2021 May;593(7860):602-606
Nature 2021 May;593(7860):602-606
DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.
Zhang F, Ruan X, Ma J, Liu X, Zheng J, Liu Y, Liu L, Shen S, Shao L, Wang D, Yang C, Cai H, Li Z, Feng Z, Xue Y
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):613-630
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):613-630
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, Dou J, Jin H, Chen R, Xu M, Chen Q, Wang Y, Yu J
Nucleic acids research 2015 Sep 18;43(16):7945-60
Nucleic acids research 2015 Sep 18;43(16):7945-60
Primary microRNA precursor transcripts are localized at post-synaptic densities in adult mouse forebrain.
Lugli G, Larson J, Demars MP, Smalheiser NR
Journal of neurochemistry 2012 Nov;123(4):459-66
Journal of neurochemistry 2012 Nov;123(4):459-66
Identification of microprocessor-dependent cancer cells allows screening for growth-sustaining micro-RNAs.
Peric D, Chvalova K, Rousselet G
Oncogene 2012 Apr 19;31(16):2039-48
Oncogene 2012 Apr 19;31(16):2039-48
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DGCR8 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human DGCR8. This antibody recognizes human, mouse antigen. The DGCR8 antibody has been validated for the following applications: ELISA, WB analysis.
