orb1993809

antibody from Biorbyt

Targeting: ICAM1 BB2, CD54

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Functional assay (Data presented on provider website)

Antibody Data

Product number

orb1993809

Provider

Biorbyt

Product name

CD54 Antibody

Antibody type

Monoclonal

Description

CD54 (ICAM-1) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.

Reactivity

Mouse

Conjugate

Unconjugated

Antibody clone number

YN1/1.7.4

Vial size

0.1 mg

Concentration

1 mg/ml

Storage

Store at 2-8°C. Do not freeze.