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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- NB110-40766 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-40766, RRID:AB_2129272
- Product name
- Rabbit Polyclonal CD11b/c Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation.
Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation.
Cross-talk between microglia and neurons regulates HIV latency.
Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice.
Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.
Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4.
Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain.
The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy.
MCP-1 stimulates spinal microglia via PI3K/Akt pathway in bone cancer pain.
Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Involvement of the kynurenine pathway in human glioma pathophysiology.
Selective transfection of microglia in the brain using an antibody-based non-viral vector.
Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration.
Pioglitazone attenuates lung injury by modulating adipose inflammation.
Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation.
Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury.
Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.
IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
Moreno P, Cazuza RA, Mendes-Gomes J, Díaz AF, Polo S, Leánez S, Leite-Panissi CRA, Pol O
International journal of molecular sciences 2019 May 5;20(9)
International journal of molecular sciences 2019 May 5;20(9)
Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation.
Díaz AF, Polo S, Gallardo N, Leánez S, Pol O
Journal of clinical medicine 2019 Jun 21;8(6)
Journal of clinical medicine 2019 Jun 21;8(6)
Cross-talk between microglia and neurons regulates HIV latency.
Alvarez-Carbonell D, Ye F, Ramanath N, Garcia-Mesa Y, Knapp PE, Hauser KF, Karn J
PLoS pathogens 2019 Dec;15(12):e1008249
PLoS pathogens 2019 Dec;15(12):e1008249
Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice.
Ferreira-Chamorro P, Redondo A, Riego G, Leánez S, Pol O
Frontiers in pharmacology 2018;9:1332
Frontiers in pharmacology 2018;9:1332
Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.
Cruz VH, Arner EN, Wynne KW, Scherer PE, Brekken RA
Molecular metabolism 2018 Oct;16:139-149
Molecular metabolism 2018 Oct;16:139-149
Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
Riego G, Redondo A, Leánez S, Pol O
Biochemical pharmacology 2018 Feb;148:52-63
Biochemical pharmacology 2018 Feb;148:52-63
Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4.
Lu N, Li Y, Zhang Z, Xing J, Sun Y, Yao S, Chen L
Nature communications 2018 Feb 21;9(1):742
Nature communications 2018 Feb 21;9(1):742
Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain.
Ding Z, Xu W, Zhang J, Zou W, Guo Q, Huang C, Liu C, Zhong T, Zhang JM, Song Z
International journal of cancer 2017 Jan 15;140(2):411-422
International journal of cancer 2017 Jan 15;140(2):411-422
The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
Castany S, Carcolé M, Leánez S, Pol O
PloS one 2016;11(1):e0146427
PloS one 2016;11(1):e0146427
Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy.
Biktasova AK, Dudimah DF, Uzhachenko RV, Park K, Akhter A, Arasada RR, Evans JV, Novitskiy SV, Tchekneva EE, Carbone DP, Shanker A, Dikov MM
Cancer research 2015 Nov 15;75(22):4728-41
Cancer research 2015 Nov 15;75(22):4728-41
MCP-1 stimulates spinal microglia via PI3K/Akt pathway in bone cancer pain.
Jin D, Yang JP, Hu JH, Wang LN, Zuo JL
Brain research 2015 Mar 2;1599:158-67
Brain research 2015 Mar 2;1599:158-67
Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Massó-Vallés D, Jauset T, Serrano E, Sodir NM, Pedersen K, Affara NI, Whitfield JR, Beaulieu ME, Evan GI, Elias L, Arribas J, Soucek L
Cancer research 2015 Apr 15;75(8):1675-81
Cancer research 2015 Apr 15;75(8):1675-81
Involvement of the kynurenine pathway in human glioma pathophysiology.
Adams S, Teo C, McDonald KL, Zinger A, Bustamante S, Lim CK, Sundaram G, Braidy N, Brew BJ, Guillemin GJ
PloS one 2014;9(11):e112945
PloS one 2014;9(11):e112945
Selective transfection of microglia in the brain using an antibody-based non-viral vector.
Malmevik J, Rogers ML, Nilsson M, Nakanishi Y, Rush RA, Sims NR, Muyderman H
Brain research 2014 Oct 24;1586:12-22
Brain research 2014 Oct 24;1586:12-22
Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration.
Berbegall AP, Villamón E, Tadeo I, Martinsson T, Cañete A, Castel V, Navarro S, Noguera R
Neoplasia (New York, N.Y.) 2014 Jun;16(6):471-80
Neoplasia (New York, N.Y.) 2014 Jun;16(6):471-80
Pioglitazone attenuates lung injury by modulating adipose inflammation.
Kutsukake M, Matsutani T, Tamura K, Matsuda A, Kobayashi M, Tachikawa E, Uchida E
The Journal of surgical research 2014 Jun 15;189(2):295-303
The Journal of surgical research 2014 Jun 15;189(2):295-303
Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation.
Shi X, Chen X, Li X, Lan X, Zhao C, Liu S, Huang H, Liu N, Liao S, Song W, Zhou P, Wang S, Xu L, Wang X, Dou QP, Liu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 1;20(1):151-63
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 1;20(1):151-63
Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury.
Yen YT, Yang HR, Lo HC, Hsieh YC, Tsai SC, Hong CW, Hsieh CH
Surgery 2013 May;153(5):689-98
Surgery 2013 May;153(5):689-98
Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.
Hervera A, Leánez S, Motterlini R, Pol O
Anesthesiology 2013 May;118(5):1180-97
Anesthesiology 2013 May;118(5):1180-97
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
Hervera A, Leánez S, Negrete R, Motterlini R, Pol O
PloS one 2012;7(8):e43693
PloS one 2012;7(8):e43693
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.
Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2011 Sep 27;108(39):16369-74
Proceedings of the National Academy of Sciences of the United States of America 2011 Sep 27;108(39):16369-74
IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.
Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5333-43
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5333-43
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
Chakrabarty P, Jansen-West K, Beccard A, Ceballos-Diaz C, Levites Y, Verbeeck C, Zubair AC, Dickson D, Golde TE, Das P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Feb;24(2):548-59
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Feb;24(2):548-59
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CD11b/c Antibody [NB110-40766] - Analysis of CD11b/c in Raw 264.7 whole cell lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: CD11b/c Antibody [NB110-40766] - Staining of human bone marrow, myeloid precursors.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: CD11b/c Antibody [NB110-40766] - 10 um Cryosection of murine acute brain slices stained with CD11b/c antibody (1:300 = 3.3 ug/ml) and Alexa Fluor 555 donkey anti rabbit IgG. Antibody shows specific staining, but the background is quite heavy. Image from verified customer review.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: CD11b/c Antibody [NB110-40766] - A surface stain was performed on RAW 264.7 with NB110-40766 and a matched isotype control. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature, followed by Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, DyLight 550.
