PAB12994

antibody from Abnova Corporation

Targeting: HAP1 HAP2, hHLP1, HIP5, HLP

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12994

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12994, RRID:AB_10561114

Product name

HAP1 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of HAP1.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.

Borrell-Pagès M, Zala D, Humbert S, Saudou F
Cellular and molecular life sciences : CMLS 2006 Nov;63(22):2642-60

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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.

Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F
Cell 2004 Jul 9;118(1):127-38

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Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin.

Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA
Human molecular genetics 1997 Dec;6(13):2205-12

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of HAP1 in mouse brain tissue lysate with HAP1 polyclonal antibody (Cat # PAB12994) at (A) 0.5 and (B) 1 ug/mL .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemistry of HAP1 in human brain tissue with HAP1 polyclonal antibody (Cat # PAB12994) at 2.5 ug/mL .

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)