CABT-B10383

antibody from Creative Diagnostics

Targeting: HAP1 HAP2, hHLP1, HIP5, HLP

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B10383

Provider

Creative Diagnostics

Product name

Mouse anti-Rat Hap1 monoclonal antibody, clone 2C7

Antibody type

Monoclonal

Description

Huntingtons disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Reactivity

Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2C7

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.