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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- NB110-74569 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-74569, RRID:AB_1050126
- Product name
- Mouse Monoclonal HAP1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. This is specific for isoforms A and B.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome.
Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform.
Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse.
A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain.
A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain.
Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function.
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.
Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.
Xiang J, Yang S, Xin N, Gaertig MA, Reeves RH, Li S, Li XJ
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 14;114(7):E1224-E1233
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 14;114(7):E1224-E1233
Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform.
Corradini E, Burgers PP, Plank M, Heck AJ, Scholten A
The Journal of biological chemistry 2015 Mar 20;290(12):7887-96
The Journal of biological chemistry 2015 Mar 20;290(12):7887-96
Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse.
Corradini E, Vallur R, Raaijmakers LM, Feil S, Feil R, Heck AJ, Scholten A
Molecular & cellular proteomics : MCP 2014 Aug;13(8):2004-16
Molecular & cellular proteomics : MCP 2014 Aug;13(8):2004-16
A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain.
Torre ER, Coleman S, Yi H, Gutekunst CA
Journal of neuroscience methods 2003 May 30;125(1-2):27-32
Journal of neuroscience methods 2003 May 30;125(1-2):27-32
A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain.
Torre ER, Coleman S, Yi H, Gutekunst CA
Journal of neuroscience methods 2003 May 30;125(1-2):27-32
Journal of neuroscience methods 2003 May 30;125(1-2):27-32
Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function.
Gutekunst CA, Torre ER, Sheng Z, Yi H, Coleman SH, Riedel IB, Bujo H
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003 Jun;51(6):841-52
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003 Jun;51(6):841-52
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
Tang TS, Tu H, Chan EY, Maximov A, Wang Z, Wellington CL, Hayden MR, Bezprozvanny I
Neuron 2003 Jul 17;39(2):227-39
Neuron 2003 Jul 17;39(2):227-39
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
Tang TS, Tu H, Chan EY, Maximov A, Wang Z, Wellington CL, Hayden MR, Bezprozvanny I
Neuron 2003 Jul 17;39(2):227-39
Neuron 2003 Jul 17;39(2):227-39
Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.
Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR
Human molecular genetics 2002 Apr 15;11(8):945-59
Human molecular genetics 2002 Apr 15;11(8):945-59
Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.
Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR
Human molecular genetics 2002 Apr 15;11(8):945-59
Human molecular genetics 2002 Apr 15;11(8):945-59
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: HAP1 Antibody (1B6) [NB110-74569] - Analysis of HAP1 using Lane 1: mouse brain lysate and Lane 2: human brain lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: HAP1 Antibody (1B6) [NB110-74569] - Detection of HAP1 in mouse brain lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: HAP1 Antibody (1B6) [NB110-74569] - Staining of rat hypothalamus.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: HAP1 Antibody (1B6) [NB110-74569] - Intracellular flow cytometric staining of 1 x 10^6 MCF-7 cells using HAP1 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used.
