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Targeting: CD44
CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- ABIN1672915 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD44 (CD44) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the N-terminal of human CD44, different from the related rat sequence by three amino acids.Immunogen affinity purified.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references CD44 regulates arteriogenesis in mice and is differentially expressed in patients with poor and good collateralization.
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth.
A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding.
Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.
van Royen N, Voskuil M, Hoefer I, Jost M, de Graaf S, Hedwig F, Andert JP, Wormhoudt TA, Hua J, Hartmann S, Bode C, Buschmann I, Schaper W, van der Neut R, Piek JJ, Pals ST
Circulation 2004 Apr 6;109(13):1647-52
Circulation 2004 Apr 6;109(13):1647-52
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth.
Sherman L, Wainwright D, Ponta H, Herrlich P
Genes & development 1998 Apr 1;12(7):1058-71
Genes & development 1998 Apr 1;12(7):1058-71
A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding.
Telen MJ, Udani M, Washington MK, Levesque MC, Lloyd E, Rao N
The Journal of biological chemistry 1996 Mar 22;271(12):7147-53
The Journal of biological chemistry 1996 Mar 22;271(12):7147-53
Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.
Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI
Proceedings of the National Academy of Sciences of the United States of America 1992 Dec 15;89(24):12160-4
Proceedings of the National Academy of Sciences of the United States of America 1992 Dec 15;89(24):12160-4
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Supportive validation
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- Experimental details
- WB: HELA Cell Lysate
Supportive validation
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- ICC: HELA Cell
Supportive validation
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- IHC(P): Human Oesophagus Squama Cancer Tissue
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- IHC(P): Human Intestinal Cancer Tissue
