BBA11
antibody from R&D Systems
Targeting: CD44
CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- BBA11 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CD44v3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CD44v3 in Western blots. The specificity of monoclonal antibody clone 3G5 was determined by FACS analysis on a panel of CD44 transfected COS cells, and was deduced to be specific for CD44 protein isoforms containing human variant exon 3 (9).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3G5
- Vial size
- 200 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment.
MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis.
Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection.
Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas.
CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas.
Tirella A, Kloc-Muniak K, Good L, Ridden J, Ashford M, Puri S, Tirelli N
International journal of pharmaceutics 2019 Apr 20;561:114-123
International journal of pharmaceutics 2019 Apr 20;561:114-123
MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis.
Yoo SA, Leng L, Kim BJ, Du X, Tilstam PV, Kim KH, Kong JS, Yoon HJ, Liu A, Wang T, Song Y, Sauler M, Bernhagen J, Ritchlin CT, Lee P, Cho CS, Kim WU, Bucala R
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 6;113(49):E7917-E7926
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 6;113(49):E7917-E7926
Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
Bailón E, Ugarte-Berzal E, Amigo-Jiménez I, Van den Steen P, Opdenakker G, García-Marco JA, García-Pardo A
Journal of leukocyte biology 2014 Aug;96(2):185-99
Journal of leukocyte biology 2014 Aug;96(2):185-99
Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection.
Shannon-Lowe C, Rowe M
PLoS pathogens 2011 May;7(5):e1001338
PLoS pathogens 2011 May;7(5):e1001338
Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC
Cancer research 2003 Feb 15;63(4):887-92
Cancer research 2003 Feb 15;63(4):887-92
CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas.
Dingemans KP, Ramkema MD, Pals ST
Laboratory investigation; a journal of technical methods and pathology 2002 Mar;82(3):313-22
Laboratory investigation; a journal of technical methods and pathology 2002 Mar;82(3):313-22
CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas.
Dingemans KP, Ramkema MD, Pals ST
Laboratory investigation; a journal of technical methods and pathology 2002 Mar;82(3):313-22
Laboratory investigation; a journal of technical methods and pathology 2002 Mar;82(3):313-22
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- CD44 in Human PBMCs. CD44 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using 8 µg/mL Mouse Anti-Human CD44 v3 Monoclonal Antibody (Catalog # BBA11) for 3 hours at room temperature. Cells were stained (red) and counterstained (green). View our protocol for Fluorescent ICC Staining of Non-adherent Cells.