FNab04821

antibody from FineTest Biotech
Targeting: LONP1 hLON, LonHS, PIM1, PRSS15
Provider product page for FNab04821
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab04821 - Provider product page
Provider
FineTest Biotech
Product name
LONP1 antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory(StAR) protein.
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
lon peptidase 1, mitochondrial
Epitope
IgG2a
Isotype
IgG
Antibody clone number
9H10
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
LONP1 protein structure - FNab04821 shown in red.