BS3514

antibody from Bioworld Technology, Inc
Targeting: HIF1A bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8
Provider product page for BS3514
Western blot
Immunohistochemistry

Antibody data

Product number
BS3514 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3514, RRID:AB_1663164
Product name
HIF 1Ï« (K377) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 345-398 of Human HIF-1Ï«.
Description
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1Ï«, Arnt 1 (also designated HIF-1ÉÇ), EPAS-1 (also designated HIF-2Ï«) and HIF-3Ï«, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1Ï« is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HIF1A protein structure - BS3514 shown in red.