MAB3551-100

antibody from R&D Systems

Targeting: BMP2 BMP2A

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

MAB3551-100

Provider

R&D Systems

Product name

Human BMP-2 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects human BMP-2 in ELISAs and Western blots. In Western blots, this antibody shows less than 1% cross-reactivity with recombinant human (rh) BMP-3, rhBMP-4, rhBMP-5, rhBMP-6, or rhBMP-7.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

P12643


Isotype

IgG

Antibody clone number

100221

Vial size

100 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

Hurst LA, Dunmore BJ, Long L, Crosby A, Al-Lamki R, Deighton J, Southwood M, Yang X, Nikolic MZ, Herrera B, Inman GJ, Bradley JR, Rana AA, Upton PD, Morrell NW
Nature communications 2017 Jan 13;8:14079

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Osteogenic Surface Modification Based on Functionalized Poly-P-Xylylene Coating.

Chang CH, Yeh SY, Lee BH, Chen CJ, Su CT, Lin YT, Liu CL, Chen HY
PloS one 2015;10(9):e0137017

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Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade.

Du Y, Xiao Q, Yip HK
Investigative ophthalmology & visual science 2010 Jul;51(7):3764-73

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Periodontal regeneration using ex vivo autologous stem cells engineered to express the BMP-2 gene: an alternative to alveolaplasty.

Chen YL, Chen PK, Jeng LB, Huang CS, Yang LC, Chung HY, Chang SC
Gene therapy 2008 Nov;15(22):1469-77

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Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bächinger HP, Sakai LY
The Journal of biological chemistry 2008 May 16;283(20):13874-88

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Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin.

Kuns-Hashimoto R, Kuninger D, Nili M, Rotwein P
American journal of physiology. Cell physiology 2008 Apr;294(4):C994-C1003

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Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism.

Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET
Cancer research 2005 Sep 15;65(18):8274-85

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Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer.

Kayed H, Kleeff J, Keleg S, Guo J, Ketterer K, Berberat PO, Giese N, Esposito I, Giese T, Büchler MW, Friess H
International journal of cancer 2004 Jul 10;110(5):668-76