APR03956G

antibody from Leading Biology

Targeting: CTDSP2 OS4, PSR2, SCP2

Western blot (Recommended by provider)

Antibody Data

Product number

APR03956G

Provider

Leading Biology

Product name

CTDSP2 Antibody (N-term)

Antibody type

Polyclonal

Description

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.