abx028027

antibody from Abbexa

Targeting: CTDSP2 OS4, PSR2, SCP2

No application information provided.

Antibody Data

Product number

abx028027

Provider

Abbexa

Product name

CTD Small Phosphatase Like Protein 2 (CTDSP2) Antibody

Antibody type

Polyclonal

Description

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.