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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2067 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2067, RRID:AB_1574529
- Product name
- DYRK1A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of DYRK1A.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis.
DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.
Adayev T, Chen-Hwang MC, Murakami N, Lee E, Bolton DC, Hwang YW
Biochemistry 2007 Jun 26;46(25):7614-24
Biochemistry 2007 Jun 26;46(25):7614-24
Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis.
Chang HS, Lin CH, Yang CH, Yen MS, Lai CR, Chen YR, Liang YJ, Yu WC
International journal of cancer 2007 Jun 1;120(11):2377-85
International journal of cancer 2007 Jun 1;120(11):2377-85
DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.
Alvarez M, Altafaj X, Aranda S, de la Luna S
Molecular biology of the cell 2007 Apr;18(4):1167-78
Molecular biology of the cell 2007 Apr;18(4):1167-78
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of DYRK1A polyclonal antibody (Cat # PAB2067) in 293 cell line lysates (35 ug/lane). DYRK1A (arrow) was detected using the purified Polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human prostate carcinomareacted with DYRK1A polyclonal antibody (Cat # PAB2067), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
