BS1700

antibody from Bioworld Technology, Inc

Targeting: VCL

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: BS1700 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS1700, RRID:AB_1663780
Product name: Vinculin (L817) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 780-830 of Human Vinculin.
Description: Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and Ï«-actinin. In addition, vinculin, Talin and Ï«-actinin each contain Actin binding sites. Expression of vinculin and Talin has been shown to be affected by the level of Actin expression. Ï«-Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

VCL protein structure - BS1700 shown in red.