BS7280

antibody from Bioworld Technology, Inc
Targeting: VCL
Provider product page for BS7280
Western blot
Immunohistochemistry

Antibody data

Product number
BS7280 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Vinculin polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Vinculin.
Description
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and Ï«-actinin. In addition, vinculin, Talin and Ï«-actinin each contain Actin binding sites. Expression of vinculin and Talin has been shown to be affected by the level of Actin expression. Ï«-Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
VCL protein structure - BS7280 shown in red.