Tissue expression
Cell line expression
Protein structure
MSX2
Msh homeobox 2CRS2, FPP, HOX8, MSH, PFM, PFM1
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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Affinity Biosciences | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
1 references | Monoclonal |
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Biorbyt | ![]() |
Polyclonal |
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