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Protein structure
ARHGEF12
Rho guanine nucleotide exchange factor 12KIAA0382, LARG
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Top validated antibodies |
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| Proteintech Group |  22441-1-AP |
4 references | Polyclonal |
WB
EL
ICC
IHC
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| Biorbyt | orb1972575 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| LSBio | LS-B11451 |
Polyclonal |
WB
EL
IHC
|
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| NovoPro Bioscience Inc. | 112144 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| Invitrogen Antibodies | 22441-1-AP |
Polyclonal |
WB
ICC
IHC
|
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