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Protein structure
ATP6V1B2
ATPase H+ transporting V1 subunit B2ATP6B2, HO57, VATB, Vma2, VPP3
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  15097-1-AP |
9 references | Polyclonal |
WB
EL
IP
IHC
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| LSBio | LS-B6383 |
Monoclonal |
WB
EL
IHC
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| Invitrogen Antibodies | 15097-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Atlas Antibodies | HPA008147 |
2 references | Polyclonal |
WB
ICC
IHC
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| NovoPro Bioscience Inc. | 108307 |
Polyclonal |
WB
EL
IP
IHC
|
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