MA-1H5

antibody from Molecular Innovations

Targeting: VLDLR CARMQ1, CHRMQ1, VLDLRCH

ELISA (Recommended by provider)

Blocking/Neutralizing (Data presented on provider website)

Antibody Data

Product number

MA-1H5

Provider

Molecular Innovations

Product name

Anti-VLDLR

Antibody type

Monoclonal

Antigen

Recombinant protein fragment

Description

Inhibitory Anti Human VLDL receptor, clone 1H5. Monoclonal antibody produced in mouse. Useful for ELISA. Binds to an epitope on the C-terminus of VLDL receptor ligand binding domain (amino acids 191-355, UniProtKB: locus VLDLR_HUMAN, accession P98155) and blocks apoE4 binding. Purified by immobilized Protein A. IgG1 class. References: Functional domains of the very low density lipoprotein receptor: molecular analysis of ligand binding and acid-dependent ligand dissociation mechanisms. Mikhailenko I et al. Journal of Cell Science 112, 3269-3281 (1999). The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. Ruiz J et al. Journal of Lipid Research 46, 1721-1731 (2005).

Reactivity

Human

Host

Mouse

Epitope

C-terminus of VLDL receptor ligand binding domain (191-355)

Isotype

IgG

Antibody clone number

1H5

Vial size

500 µl

Concentration

2 mg/ml

Storage

-70 C