Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- 25155-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#25155-1-AP, RRID:AB_2810874
- Product name
- ATG2B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG2B antibody (Cat. #25155-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size.
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.
The autophagy protein ATG9A enables lipid mobilization from lipid droplets.
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
A conserved ATG2-GABARAP family interaction is critical for phagophore formation.
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion.
Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation.
Sakai SS, Hasegawa A, Ishimura R, Tamura N, Kageyama S, Komatsu-Hirota S, Abe M, Ling Y, Okuda S, Funayama M, Kikkawa M, Miura Y, Sakimura K, Narita I, Waguri S, Shimizu R, Komatsu M
Molecular and cellular biology 2022 Jan 20;42(1):e0002421
Molecular and cellular biology 2022 Jan 20;42(1):e0002421
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.
Lee JE, Kim N, Jung M, Mun JY, Yoo JY
Autophagy 2021 Oct 31;:1-16
Autophagy 2021 Oct 31;:1-16
The autophagy protein ATG9A enables lipid mobilization from lipid droplets.
Mailler E, Guardia CM, Bai X, Jarnik M, Williamson CD, Li Y, Maio N, Golden A, Bonifacino JS
Nature communications 2021 Nov 19;12(1):6750
Nature communications 2021 Nov 19;12(1):6750
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
Claude-Taupin A, Jia J, Bhujabal Z, Garfa-Traoré M, Kumar S, da Silva GPD, Javed R, Gu Y, Allers L, Peters R, Wang F, da Costa LJ, Pallikkuth S, Lidke KA, Mauthe M, Verlhac P, Uchiyama Y, Salemi M, Phinney B, Tooze SA, Mari MC, Johansen T, Reggiori F, Deretic V
Nature cell biology 2021 Aug;23(8):846-858
Nature cell biology 2021 Aug;23(8):846-858
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
Sun W, Li J, Zhou L, Han J, Liu R, Zhang H, Ning T, Gao Z, Liu B, Chen X, Ba Y
Theranostics 2020;10(5):1981-1996
Theranostics 2020;10(5):1981-1996
A conserved ATG2-GABARAP family interaction is critical for phagophore formation.
Bozic M, van den Bekerom L, Milne BA, Goodman N, Roberston L, Prescott AR, Macartney TJ, Dawe N, McEwan DG
EMBO reports 2020 Mar 4;21(3):e48412
EMBO reports 2020 Mar 4;21(3):e48412
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
Li Y, Yong YL, Yang M, Wang W, Qu X, Dang X, Shang D, Shao Y, Liu J, Chang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion.
Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, Chen H, Young MM, Wang HG
Cell reports 2019 Aug 13;28(7):1744-1757.e5
Cell reports 2019 Aug 13;28(7):1744-1757.e5
Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation.
Zheng JX, Li Y, Ding YH, Liu JJ, Zhang MJ, Dong MQ, Wang HW, Yu L
Autophagy 2017;13(11):1870-1883
Autophagy 2017;13(11):1870-1883
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The ATG2B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ATG2B. This antibody recognizes human antigen. The ATG2B antibody has been validated for the following applications: ELISA, WB, IHC analysis.